#aav-antithrombotic-calculator{--primary:#8637b2;--primary-dark:#6d2a94;--tint:#f3ebfa;--ink:#101123;--ink-soft:#454063;--muted:#6f6a86;--line:#e7e3ef;--line-soft:#f2eff8;--bg:#f6f4fb;--amber:#8a6508;--amber-bg:#fff7e3;--amber-line:#f0dca0;--red:#c0362c;--red-bg:#fdecea;--red-line:#f3c4bf;--green:#17714a;--green-bg:#eaf6f0;--green-line:#bfe3d0;--r-card:14px;--r-field:9px;--r-panel:10px;color:var(--ink);background:var(--bg);margin:0;padding:196px 16px 40px;font-family:-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica,Arial,sans-serif;font-size:15px;line-height:1.45}#aav-antithrombotic-calculator *,#aav-antithrombotic-calculator :before,#aav-antithrombotic-calculator :after{box-sizing:border-box}#aav-antithrombotic-calculator .aav-content{max-width:1180px;margin:0 auto;container:aavwrap/inline-size}#aav-antithrombotic-calculator a{color:var(--primary-dark)}#aav-antithrombotic-calculator :focus-visible{outline:3px solid var(--primary);outline-offset:1px}#aav-antithrombotic-calculator header.top{align-items:center;gap:12px;padding:18px 0 10px;display:flex}#aav-antithrombotic-calculator .logo{background:linear-gradient(135deg,var(--primary),#5b1e82);color:#fff;letter-spacing:.5px;border-radius:12px;flex:0 0 44px;justify-content:center;align-items:center;width:44px;height:44px;font-size:20px;font-weight:800;display:flex}#aav-antithrombotic-calculator .bname{letter-spacing:.2px;font-size:17px;font-weight:800}#aav-antithrombotic-calculator .bsub{color:var(--muted);font-size:12.5px}#aav-antithrombotic-calculator .btag{color:var(--primary-dark);letter-spacing:.4px;text-transform:uppercase;margin-left:auto;font-size:12.5px;font-weight:700}#aav-antithrombotic-calculator .titleband{border-bottom:1px solid var(--line);margin-bottom:18px;padding:6px 0 16px}#aav-antithrombotic-calculator .titleband h1{text-wrap:balance;margin:0 0 6px;font-size:26px;line-height:1.2}#aav-antithrombotic-calculator .titleband p{color:var(--ink-soft);max-width:70ch;margin:0}#aav-antithrombotic-calculator .audnote{background:var(--tint);border:1px solid var(--line);border-radius:var(--r-panel);color:var(--ink-soft);margin:0 0 18px;padding:10px 14px;font-size:13.5px}#aav-antithrombotic-calculator .modetabs{flex-wrap:wrap;gap:8px;margin:0 0 16px;display:flex}#aav-antithrombotic-calculator .modetabs button{font:inherit;border-radius:var(--r-field);min-height:44px;color:var(--ink-soft);cursor:pointer;background:#fff;border:1.5px solid #8a84a3;padding:10px 16px;font-weight:700}#aav-antithrombotic-calculator .modetabs button[aria-pressed=true]{background:var(--primary);border-color:var(--primary);color:#fff;box-shadow:inset 0 0 0 2px #fff3}#aav-antithrombotic-calculator .modetabs button:focus-visible{outline:3px solid var(--primary-dark);outline-offset:2px}#aav-antithrombotic-calculator main.grid{grid-template-columns:1fr 1fr;align-items:start;gap:18px;display:grid}#aav-antithrombotic-calculator main.grid>*{min-width:0}#aav-antithrombotic-calculator .rescol{position:sticky;top:12px}@container aavwrap (max-width:900px){#aav-antithrombotic-calculator main.grid{grid-template-columns:1fr}#aav-antithrombotic-calculator .rescol{position:static}}@media (max-width:900px){#aav-antithrombotic-calculator{padding-top:126px}#aav-antithrombotic-calculator main.grid{grid-template-columns:1fr}#aav-antithrombotic-calculator .rescol{position:static}}#aav-antithrombotic-calculator .card{border:1px solid var(--line);border-radius:var(--r-card);background:#fff;margin:0 0 16px}#aav-antithrombotic-calculator .card>.inner{padding:20px}#aav-antithrombotic-calculator .step{background:var(--tint);border-left:4px solid var(--primary);border-radius:var(--r-panel);margin:0 0 14px;padding:12px 14px}#aav-antithrombotic-calculator .step .sn{background:var(--primary);color:#fff;vertical-align:middle;border-radius:6px;justify-content:center;align-items:center;width:24px;height:24px;margin-right:8px;font-size:13px;font-weight:800;display:inline-flex}#aav-antithrombotic-calculator .step h3{vertical-align:middle;margin:0;font-size:15.5px;display:inline}#aav-antithrombotic-calculator .step .sx{color:var(--ink-soft);margin-top:4px;font-size:13px;display:block}#aav-antithrombotic-calculator .secbar{border-left:4px solid var(--primary);margin:0 0 10px;padding-left:10px;font-size:16px;font-weight:800}#aav-antithrombotic-calculator .seg{flex-wrap:wrap;gap:8px;margin:8px 0 4px;display:flex}#aav-antithrombotic-calculator .seg button{font:inherit;border-radius:var(--r-field);min-width:44px;min-height:44px;color:var(--ink-soft);cursor:pointer;background:#fff;border:1.5px solid #8a84a3;padding:9px 14px;font-weight:700}#aav-antithrombotic-calculator .seg button[aria-pressed=true]{background:var(--primary);border-color:var(--primary);color:#fff;box-shadow:inset 0 0 0 2px #fff3}#aav-antithrombotic-calculator .seg .em{margin-right:6px;font-style:normal}#aav-antithrombotic-calculator .lbl{margin:12px 0 4px;font-size:13.5px;font-weight:700;display:block}#aav-antithrombotic-calculator .hint{color:var(--muted);margin:2px 0 0;font-size:12.5px}#aav-antithrombotic-calculator input[type=text],#aav-antithrombotic-calculator select{font:inherit;color:var(--ink);border-radius:var(--r-field);background:#fff;border:1.5px solid #8a84a3;width:100%;max-width:280px;min-height:44px;padding:10px 12px;font-size:16px}#aav-antithrombotic-calculator select{max-width:100%}#aav-antithrombotic-calculator input[aria-invalid=true]{border-color:var(--red);background:var(--red-bg)}#aav-antithrombotic-calculator .fielderr{color:var(--red);margin-top:4px;font-size:13px;font-weight:600}#aav-antithrombotic-calculator .ckgrp{margin:6px 0 2px}#aav-antithrombotic-calculator .ckrow{border-radius:8px;align-items:flex-start;gap:10px;padding:7px 6px;display:flex}#aav-antithrombotic-calculator .ckrow:hover{background:var(--line-soft)}#aav-antithrombotic-calculator .ckrow input{width:20px;height:20px;accent-color:var(--primary);flex:0 0 20px;margin:2px 0 0}#aav-antithrombotic-calculator .ckrow label{cursor:pointer;flex:1;min-height:24px;padding:2px 0;display:block}#aav-antithrombotic-calculator fieldset.ckgrp{border:0;min-width:0;margin:6px 0 2px;padding:0}#aav-antithrombotic-calculator legend.grphead{padding:0}#aav-antithrombotic-calculator .ckrow .src{color:var(--muted);font-size:12px;display:block}#aav-antithrombotic-calculator .subck{border-left:2px solid var(--line);margin-left:26px;padding-left:10px}#aav-antithrombotic-calculator .grphead{color:var(--primary-dark);text-transform:uppercase;letter-spacing:.4px;margin:12px 0 2px;font-size:13px;font-weight:700}#aav-antithrombotic-calculator .result{color:#fff;border-radius:var(--r-card);background:linear-gradient(#101123,#241a3d)}#aav-antithrombotic-calculator .result .rhead{border-bottom:1px solid #fff2;padding:16px 20px 8px}#aav-antithrombotic-calculator .result .rhead h2{letter-spacing:.3px;text-transform:uppercase;color:#cbb8e8;margin:0;font-size:16px}#aav-antithrombotic-calculator .result .rbody{padding:14px 20px 20px}#aav-antithrombotic-calculator .bigcard{border-radius:var(--r-panel);background:#ffffff10;border:1px solid #ffffff26;margin:0 0 12px;padding:14px 16px}#aav-antithrombotic-calculator .bignum{text-wrap:balance;font-size:24px;font-weight:800;line-height:1.25}#aav-antithrombotic-calculator .bigsub{color:#cfc6e6;margin-top:6px;font-size:13.5px}#aav-antithrombotic-calculator .metaline{color:#cfc6e6;flex-wrap:wrap;gap:14px;margin:0 0 10px;font-size:13px;display:flex}#aav-antithrombotic-calculator .metaline b{color:#fff}#aav-antithrombotic-calculator .drugcard{border-radius:var(--r-panel);background:#ffffff0d;border:1px solid #fff2;margin:0 0 10px;padding:12px 14px}#aav-antithrombotic-calculator .drugcard h4{margin:0 0 2px;font-size:15.5px}#aav-antithrombotic-calculator .drugcard .dclass{color:#cbb8e8;text-transform:uppercase;letter-spacing:.4px;margin:0 0 8px;font-size:12px}#aav-antithrombotic-calculator .working{white-space:pre-wrap;word-break:break-word;background:#00000042;border-radius:8px;margin:6px 0;padding:8px 10px;font-family:ui-monospace,SFMono-Regular,Menlo,Consolas,monospace;font-size:13.5px;overflow-x:auto}#aav-antithrombotic-calculator .working b{color:#ffd9a8}#aav-antithrombotic-calculator .dmeta{color:#d9d2ec;margin:6px 0 0;font-size:13px}#aav-antithrombotic-calculator .dmeta b{color:#fff}#aav-antithrombotic-calculator .result :focus-visible{outline-offset:1px;outline:3px solid #fff}#aav-antithrombotic-calculator .fpair{grid-template-columns:1fr 1fr;align-items:start;gap:0 14px;display:grid}#aav-antithrombotic-calculator .fpair>label.lbl{grid-row:1}#aav-antithrombotic-calculator .fpair>input{grid-row:2}#aav-antithrombotic-calculator .fpair>p.hint,#aav-antithrombotic-calculator .fpair>p.fielderr{grid-row:3;max-width:34ch}@container aavwrap (max-width:520px){#aav-antithrombotic-calculator .fpair{grid-template-columns:1fr}#aav-antithrombotic-calculator .fpair>*{grid-row:auto}}@media (max-width:520px){#aav-antithrombotic-calculator .fpair{grid-template-columns:1fr}#aav-antithrombotic-calculator .fpair>*{grid-row:auto}}#aav-antithrombotic-calculator .glance{border-radius:var(--r-panel);background:#ffffff14;border:1px solid #fff3;margin:0 0 10px;padding:10px 14px 12px}#aav-antithrombotic-calculator .glance-head{letter-spacing:.4px;text-transform:uppercase;color:#cbb8e8;margin:0 0 4px;font-size:12px}#aav-antithrombotic-calculator .glance-list{margin:0;padding-left:20px}#aav-antithrombotic-calculator .glance-list li{margin:0 0 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details.fsec[open]>summary:after{transform:translateY(-30%)rotate(225deg)}#aav-antithrombotic-calculator .fsech{color:#e8dcff;margin:0;font-size:15.5px;font-weight:700;display:block}#aav-antithrombotic-calculator .fsum{color:#cfc6e6;margin-top:2px;font-size:13px;font-weight:400;display:block}#aav-antithrombotic-calculator .fsecintro{color:#cfc6e6;margin:0 0 8px}#aav-antithrombotic-calculator details.cdet{margin-top:6px}#aav-antithrombotic-calculator details.cdet>summary{cursor:pointer;color:#cbb8e8;background:#ffffff0d;border:1px solid #fff3;border-radius:999px;align-items:center;min-height:32px;padding:0 10px;font-size:12.5px;font-weight:700;list-style:none;display:inline-flex}#aav-antithrombotic-calculator details.cdet>summary::-webkit-details-marker{display:none}#aav-antithrombotic-calculator details.cdet>summary:after{content:"+";margin-left:6px;font-size:14px}#aav-antithrombotic-calculator details.cdet[open]>summary:after{content:"−"}#aav-antithrombotic-calculator 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.cki:hover{background:#ffffff0d}#aav-antithrombotic-calculator .cki input[type=checkbox]{accent-color:#b98cff;flex:0 0 20px;width:20px;height:20px;margin:0}#aav-antithrombotic-calculator .cki .ckt{flex:1;padding:6px 0;font-size:13.5px}#aav-antithrombotic-calculator .cki.done .ckt{color:#c9f0dc}#aav-antithrombotic-calculator .cki input[type=time]{font:inherit;color:#fff;background:#ffffff14;border:1px solid #fff3;border-radius:7px;width:auto;min-height:32px;padding:4px 6px;font-size:16px}#aav-antithrombotic-calculator .cki input[type=time]::-webkit-calendar-picker-indicator{filter:invert();opacity:.7}#aav-antithrombotic-calculator .ckl-head{align-items:center;gap:10px;display:flex}#aav-antithrombotic-calculator .ckl-head .prog{color:#cfc6e6;text-transform:none;letter-spacing:0;margin-left:auto;font-size:12.5px;font-weight:400}#aav-antithrombotic-calculator .fsum .done{color:#c9f0dc}@container aavwrap (max-width:640px){#aav-antithrombotic-calculator .ckl{grid-template-columns:1fr}}@media (max-width:640px){#aav-antithrombotic-calculator .ckl{grid-template-columns:1fr}}#aav-antithrombotic-calculator details.indet{border:1px solid var(--line);border-radius:var(--r-panel);background:#fff;margin:10px 0 0}#aav-antithrombotic-calculator details.indet>summary{cursor:pointer;min-height:44px;color:var(--primary-dark);align-items:center;padding:10px 36px 10px 12px;font-size:13.5px;font-weight:700;list-style:none;display:flex;position:relative}#aav-antithrombotic-calculator details.indet>summary::-webkit-details-marker{display:none}#aav-antithrombotic-calculator details.indet>summary:after{content:"";border-right:2.5px solid var(--primary);border-bottom:2.5px solid var(--primary);width:9px;height:9px;position:absolute;top:50%;right:14px;transform:translateY(-70%)rotate(45deg)}#aav-antithrombotic-calculator details.indet[open]>summary:after{transform:translateY(-30%)rotate(225deg)}#aav-antithrombotic-calculator details.indet>.inin{padding:0 12px 10px}#aav-antithrombotic-calculator .casebar{flex-wrap:wrap;gap:8px;margin:0 0 10px;display:flex}#aav-antithrombotic-calculator .casebar button{font:inherit;border-radius:var(--r-field);min-height:40px;color:var(--ink-soft);cursor:pointer;background:#fff;border:1.5px solid #8a84a3;padding:6px 12px;font-size:13px;font-weight:700}#aav-antithrombotic-calculator .casebar button:hover{background:var(--line-soft)}#aav-antithrombotic-calculator .chips{flex-wrap:wrap;gap:6px;margin:8px 0 6px;display:flex}#aav-antithrombotic-calculator .chip{border:1px solid;border-radius:999px;align-items:center;min-height:30px;padding:0 10px;font-size:12.5px;font-weight:700;display:inline-flex}#aav-antithrombotic-calculator .chip.ok{color:#c9f0dc;background:#0f3d29;border-color:#2c7a53}#aav-antithrombotic-calculator .chip.amber{color:#ffe9b3;background:#4a3a08;border-color:#9c8330}#aav-antithrombotic-calculator .chip.red{color:#ffd7d0;background:#5b1712;border-color:#a33a2f}#aav-antithrombotic-calculator 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.warn.amber{background:var(--amber-bg);border-color:var(--amber-line);border-left-color:var(--amber);color:#5c4304}#aav-antithrombotic-calculator .warn.info{background:var(--line-soft);border-color:var(--line);border-left-color:var(--ink-soft);color:var(--ink-soft)}#aav-antithrombotic-calculator .warn.ok{background:var(--green-bg);border-color:var(--green-line);border-left-color:var(--green);color:#0f5636}#aav-antithrombotic-calculator .result .warn.red{color:#ffd7d0;background:#5b1712;border-color:#a33a2f}#aav-antithrombotic-calculator .result .warn.amber{color:#ffe9b3;background:#4a3a08;border-color:#9c8330}#aav-antithrombotic-calculator .result .warn.info{color:#e4ddf5;background:#ffffff12;border-color:#fff3 #fff3 #fff3 #cbb8e8}#aav-antithrombotic-calculator .result .warn.ok{color:#c9f0dc;background:#0f3d29;border-color:#2c7a53}#aav-antithrombotic-calculator .actions{flex-wrap:wrap;gap:8px;margin-top:12px;display:flex}#aav-antithrombotic-calculator .abtn{font:inherit;border-radius:var(--r-field);color:#fff;cursor:pointer;background:#ffffff14;border:1.5px solid #fff7;min-height:44px;padding:9px 14px;font-weight:700}#aav-antithrombotic-calculator .abtn:hover{background:#ffffff26}#aav-antithrombotic-calculator .disclaimer{background:var(--amber-bg);border:1px solid var(--amber-line);border-left:4px solid var(--amber);border-radius:var(--r-panel);color:#5c4304;margin:16px 0;padding:12px 14px;font-size:13px}#aav-antithrombotic-calculator .seo{margin-top:26px}#aav-antithrombotic-calculator .seo h2{margin:26px 0 8px;font-size:20px}#aav-antithrombotic-calculator .seo h3{margin:18px 0 6px;font-size:16.5px}#aav-antithrombotic-calculator .seo p,#aav-antithrombotic-calculator .seo li{color:var(--ink-soft);max-width:75ch}#aav-antithrombotic-calculator .quickans{border:1px solid var(--line);border-left:4px solid var(--primary);border-radius:var(--r-panel);background:#fff;margin:0 0 8px;padding:14px 16px}#aav-antithrombotic-calculator 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details.indet>summary{color:var(--color-brand-deep);font-size:13.5px}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .casebar button{border:1.5px solid var(--color-lilac-line);background:var(--color-card);min-height:44px;color:var(--color-ink);border-radius:999px;padding:10px 18px;font-size:13.5px;font-weight:600;transition:border-color .2s,background .2s,color .2s}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .casebar button:hover{border-color:var(--color-brand);background:var(--color-card);color:var(--color-brand)}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .warn{border-radius:14px;padding:12px 15px;font-size:13px;line-height:1.5}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator #aav-integrity{margin:26px 0 0}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .rescol{position:static}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .result{background:linear-gradient(180deg, var(--color-night), var(--color-plum));border-radius:22px}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .result .rbody{padding:20px 22px 22px}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .result .bigcard,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .result .drugcard,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .result .glance{border-radius:16px}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .result .working{border-radius:12px}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .result .jumpbar{top:var(--tf-toolbar-offset,84px);background:var(--color-night)}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .abtn{background:#ffffff1a;border:1.5px solid #ffffff6b;border-radius:999px;min-height:44px;padding:11px 18px;font-size:13.5px;font-weight:600;transition:background .2s,border-color .2s}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .abtn:hover{background:#fff3;border-color:#ffffffbf}s-antithrombotic-calculator[data-tool-root] #tool-card:has(#aav-rbody:empty) .tf-toolbar-row :is(#aav-copy,#aav-note,#aav-print,#aav-email,#aav-dl){opacity:.62}s-antithrombotic-calculator[data-tool-root] #aav-pinbar:not(.alert):not(.caution){background:var(--color-night)}s-antithrombotic-calculator[data-tool-root] #aav-pinbar.caution{background:color-mix(in srgb, var(--color-triage-amber-ink) 45%, var(--color-night))}s-antithrombotic-calculator[data-tool-root] #aav-pinbar.alert{background:color-mix(in srgb, var(--color-triage-red) 40%, var(--color-night))}s-antithrombotic-calculator[data-tool-root] #aav-pinbar .pb-jump{border-radius:999px;min-height:44px;font-weight:600}s-antithrombotic-calculator[data-tool-root] #aav-pinbar:not(.alert) .pb-jump{background:var(--color-brand)}s-antithrombotic-calculator[data-tool-root] #aav-pinbar.alert .pb-jump{background:var(--color-triage-red)}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .seo{margin-top:0}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .quickans{border:1px solid var(--color-lilac-line);border-left:4px solid var(--color-brand);background:var(--color-lilac-ghost);border-radius:16px}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .toc a{border:1.5px solid var(--color-lilac-line);background:var(--color-lilac-fill);min-height:44px;color:var(--color-brand-deep);border-radius:999px;font-weight:600;transition:border-color .2s,background .2s}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .toc a:hover{border-color:var(--color-brand);background:var(--color-lilac)}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator details.refsec,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .mono,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .tblwrap{border:1px solid var(--color-lilac-line);border-radius:16px}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator details.refsec[open]{background:var(--color-lilac-ghost)}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator table.dosetable th{background:var(--color-lilac);color:var(--color-brand-deep)}@media (max-width:560px){s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .modetabs button,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .seg button,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .casebar button,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .abtn,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .cki input[type=time]{min-height:44px}s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .modetabs{grid-template-columns:1fr}}@media (prefers-reduced-motion:reduce){s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .modetabs button,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .seg button,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .casebar button,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .ckrow,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .jumpres a,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .toc a,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator .abtn,s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator input[type=text],s-antithrombotic-calculator[data-tool-root] #aav-antithrombotic-calculator select{transition:none}}