In this article
Staphylococcal (Staph) Infections in Cats: Vet Guide 2025 🐱🧴
By Dr. Duncan Houston, BVSc
🔍 Introduction
Staphylococcus are gram-positive cocci that naturally inhabit feline skin, nose and upper respiratory tract. They often live harmlessly—until skin damage, immune compromise, or allergy allows them to overgrow and cause infection. Common strains include S. pseudintermedius, S. felis, and occasionally MRSA, which can pose zoonotic risks :contentReference[oaicite:3]{index=3}.
- Opportunistic infections arise from wounds, skin irritations, ear or eye disease—even fungal or allergic triggers :contentReference[oaicite:4]{index=4}.
- Any age cat may be affected; kittens, seniors, and immunocompromised cats are at higher risk :contentReference[oaicite:5]{index=5}.
1. Clinical Presentations
- Skin & abscesses: boils, pustules, cellulitis, draining tracts—often from bite wounds or allergies :contentReference[oaicite:6]{index=6}.
- Pyoderma: itchy, inflamed, pus-filled lesions often accompanied by hair loss :contentReference[oaicite:7]{index=7}.
- Otitis externa: ear canal infections with swelling, pain, discharge :contentReference[oaicite:8]{index=8}.
- Ocular infections: conjunctivitis, keratitis, periocular swelling :contentReference[oaicite:9]{index=9}.
- Respiratory & systemic: nasal discharge, coughing, fever, lethargy, bacteremia in severe cases :contentReference[oaicite:10]{index=10}.
- MRSA/MRSP: antibiotic-resistant types occasionally transmitted between cats and humans :contentReference[oaicite:11]{index=11}.
2. Diagnosis
- History & exam: evaluate lesions, chronic allergies, trauma.
- Cytology & culture: skin/ear/ocular swabs to identify staph species and antibiotic susceptibility :contentReference[oaicite:12]{index=12}.
- Blood testing: CBC/chem to assess systemic illness if fever or lethargy present.
- Imaging or biopsy: for deep or recurrent lesions.
- Allergy or endocrine testing: if secondary infection is suspected.
3. Treatment Strategies
a. Topical care
- Medicated shampoos or wipes containing chlorhexidine, benzoyl peroxide, or mupirocin :contentReference[oaicite:13]{index=13}.
- Topical creams or gels on localized pustules or wounds.
b. Systemic antibiotics
- Guided by culture and sensitivity.
- Options include clindamycin, cephalexin, Clavamox, trimethoprim‑sulfa (3–8 weeks) :contentReference[oaicite:14]{index=14}.
- MRSA/MRSP require specialized antibiotic regimens.
c. Supportive care
- Wound cleaning, ear flushes, ocular drops.
- Pain relief (NSAIDs, gabapentin) and hydration support.
- Address underlying factors: treat allergies, endocrine disorders, or remove foreign material.
4. Zoonotic Considerations
- MRSA and some staph species can spread between cats and humans, especially with skin breaks or immunocompromised individuals :contentReference[oaicite:15]{index=15}.
- Practice good hygiene: wash hands after handling lesions, clean bedding and environment regularly.
- Immunosuppressed household members should take extra precautions.
5. Prognosis & Follow‑Up
- Most cases resolve with appropriate treatment; chronic or resistant infections require longer therapy.
- Recheck cultures 7–10 days into therapy and before stopping antibiotics.
- Manage underlying conditions to prevent recurrence.
6. Prevention & Hygiene
- Keep skin and ear canals clean and dry.
- Promptly treat wounds and maintain flea/allergy control.
- Ensure balanced nutrition and timely vaccinations to support immunity.
- Sanitize bowls, bedding, carriers; isolate infected cats from others and humans until resolved.
7. Role of Ask A Vet Remote Support
- 📸 Upload lesion or discharge photos for remote assessment and triage.
- 💊 Medication reminders and dosage tracking.
- 🧭 Guidance on hygiene measures, when to re-culture, and environmental cleaning.
- 📅 Appointment scheduling reminders and progress tracking.
8. FAQs
Can I catch staph from my cat?
Yes—especially MRSA—from wounds or broken skin. Practice good hygiene and speak to your vet about zoonotic risk :contentReference[oaicite:16]{index=16}.
How long do antibiotics take?
Treatment is typically 3–8 weeks, depending on severity and culture results.
What if the infection returns?
Recheck cultures, evaluate for underlying allergy, immune or endocrine issues.
Are topical treatments enough?
For mild, localized infections—yes. But deeper or widespread infections need systemic antibiotics.
Conclusion
Staph infections in cats are common, opportunistic, and treatable when diagnosed early. With targeted culture‑based antibiotic therapy, proper hygiene, and managing underlying triggers—with remote guidance from **Ask A Vet**—most cats recover fully. Global transmission of resistant strains highlights the importance of culture-driven treatment and hand‑hygiene protocols 🐾📲.
If your cat shows swelling, discharge, fever, or recurring skin or ear issues—especially following injury or allergies—seek vet care. You can also begin with Ask A Vet consults and photo assessment to guide your next steps.