Cutaneous & Internal Papillomatosis in Birds: A Vet’s 2025 Guide 🐦🩺

By Dr Duncan Houston BVSc – avian veterinarian & founder of Ask A Vet 🩺🐾

Papillomatosis in birds refers to benign, wart-like growths—**cutaneous** (on skin and beak) or **internal** (within the mouth, crop, proventriculus, cloaca, or intestines). While skin lesions are cosmetic, internal ones can impair eating, breathing, or defecation. Caused by papillomaviruses or herpesviruses, these growths tend to *wax and wane* and may predispose birds to infections or even cancer in the liver and pancreas :contentReference[oaicite:3]{index=3}.

1. 🌱 What is Papillomatosis?

• Cutaneous type: cauliflower-like warts on unfeathered skin—especially legs, feet, beak, eyelids :contentReference[oaicite:4]{index=4}.
• Internal type: papilloma masses in digestive/respiratory tracts, commonly cloaca or oral cavity :contentReference[oaicite:5]{index=5}.
• Likely viral origins: papillomavirus or Pacheco‑type herpesvirus; contagion occurs via bird-to-bird contact or contaminated surfaces :contentReference[oaicite:6]{index=6}.

2. 🚩 Clinical Signs

• Skin lesions: raised, fleshy, often on legs/face—may bleed or crack :contentReference[oaicite:7]{index=7}.
• Swallowing/breathing issues: oral lesions → dysphagia, regurgitation, wheezing :contentReference[oaicite:8]{index=8}.
• Cloacal signs: strain to defecate, blood-tinged or foul droppings, cloaca prolapse :contentReference[oaicite:9]{index=9}.
• Weight loss, anorexia, chronic illness: seen with internal lesions affecting digestion or respiration :contentReference[oaicite:10]{index=10}.

3. 🔬 Diagnosis

• Visual exam: skin warts and flipping the cloaca to visually inspect internal masses :contentReference[oaicite:11]{index=11}.
• Endoscopy/Radiographs: for visualizing internal growths in mouth, crop, or cloaca.
• Biopsy & histopathology: confirm papilloma tissue (hyperkeratosis, papillomatosis) and differentiate benign from malignant folds :contentReference[oaicite:12]{index=12}.
• PCR/viral testing: detect viral DNA in swabs from lesions or cloacal/oral samples :contentReference[oaicite:13]{index=13}.
• Bloodwork: to assess for secondary infection or signs of systemic disease :contentReference[oaicite:14]{index=14}.

4. ⚙️ Treatment Options

4.1 When Surgery or Cautery Is Needed

• Remove lesions that interfere with vital functions: cautery, radiosurgery, cryotherapy, or scalpel excision :contentReference[oaicite:15]{index=15}.
• Skin lesions often recur and require multiple treatments; internal lesions need careful planning to prevent tissue damage :contentReference[oaicite:16]{index=16}.
• Silver nitrate can cauterize cloacal papillomas, but protocols and recurrence rates vary :contentReference[oaicite:17]{index=17}.

4.2 Supportive Care

• Antibiotics to prevent secondary infection from ulcerated lesions, especially post-removal :contentReference[oaicite:18]{index=18}.
• Analgesics and local wound care to ease discomfort :contentReference[oaicite:19]{index=19}.
• High-vitamin‑A diet to support mucosal healing :contentReference[oaicite:20]{index=20}.

4.3 Monitoring and Long-Term Management

• Regular rechecks to identify recurrences early.
• Isolation/quarantine of infected birds to prevent spread to others :contentReference[oaicite:21]{index=21}.
• Consider surgical lesion removal before breeding or periods of immunosuppression :contentReference[oaicite:22]{index=22}.
• Use of capsaicin-rich feed (e.g., hot peppers) has anecdotal benefit in lesion reduction :contentReference[oaicite:23]{index=23}.

5. 🛡 Prevention Strategies

• Quarantine new birds for ≥ 90 days before integration :contentReference[oaicite:24]{index=24}.
• Maintain excellent hygiene of perches, food bowls, and surfaces :contentReference[oaicite:25]{index=25}.
• Avoid communal housing of infected birds; use outdoor aviaries or strict airflow separation :contentReference[oaicite:26]{index=26}.
• Vaccines are not available; genetic and husbandry methods are key in breeding programs :contentReference[oaicite:27]{index=27}.

6. 📱 Role of Ask A Vet

• Interpret lesion photos and videos for triage and urgency advice.
• Guide whether surgery or cautery is needed and recommend timing.
• Support post-removal antibiotic and nutrition protocols.
• Advise on quarantine measures and breeding advice for papilloma-positive birds.

7. 🧠 Summary Table

🧡 Final Takeaways

• Papillomatosis comprises benign warts—either external or internal—that can affect function and quality of life.
• Diagnosis requires endoscopic or biopsy confirmation due to overlap with other diseases.
• Lesions are removed when necessary, with recurrence being common.
• Supportive care—antibiotics, pain relief, nutrition—is essential post-treatment.
• Strict hygiene, quarantine, and breeding practices help prevent spread.
• Ask A Vet provides expert support in diagnosing, planning treatment, and advising long-term flock care.

If your bird has warty growths, difficulty eating, breathing, or defecating, reach out to your avian veterinarian or connect via the Ask A Vet app. With timely diagnosis, thoughtful treatment, and preventative measures, many birds enjoy improved comfort and function. 🐾