Inflammatory Bowel Disease (IBD) in Cats: Vet Guide 🐱🍽️ 2025

By Dr Duncan Houston BVSc, veterinarian & founder of Ask A Vet.

Inflammatory Bowel Disease (IBD) describes chronic gastrointestinal inflammation—typically in the stomach, small intestine, and/or colon—affecting digestion, nutrient absorption, and quality of life. In this 2025 guide, we’ll explore:

• 🔍 Definitions & types of feline IBD
• 🧬 Underlying causes and risk factors
• 🚨 Signs & clinical presentation
• 🧪 Diagnostic workflows
• 💊 Treatment and management strategies
• 🥗 Diet planning and nutrition tips
• 🏠 Home care and monitoring
• 🤝 Roles of Ask A Vet, Woopf & Purrz

🔍 What Is IBD?

IBD refers to chronic inflammation of the gastrointestinal (GI) tract—commonly the stomach, small intestine, or colon. It arises when immune cells (lymphocytes, plasma cells, eosinophils) infiltrate the GI wall, disrupting digestion and absorption, causing discomfort and systemic effects.

Common feline types include:

• Lymphocytic-plasmacytic IBD: most common form, with lymphocyte and plasma cell infiltration.
• Eosinophilic IBD: often allergic in origin.
• Mixed or granulomatous: less common.

🧬 Causes & Risk Factors

IBD is multifactorial, involving:

• Diet sensitivity or allergies: proteins, gluten, additives.
• Gut dysbiosis: imbalance of healthy gut bacteria.
• Chronic infection: Helicobacter, parasites (Giardia, Tritrichomonas).
• Immune dysregulation: inappropriate immune response to normal flora or food antigens.
• Genetic predisposition: certain breeds (e.g. Cornish Rex, Siamese).
• Concurrent diseases: pancreatitis, cholangitis (“triaditis”).

🚨 Signs & Presentation

Signs vary depending on which GI region is involved:

• Small intestinal IBD: chronic vomiting, diarrhea, weight loss, poor coat.
• Large intestinal IBD: frequent soft stools, mucus, straining in litterbox.
• Mixed forms: vomiting, variable stool consistency.
• General symptoms: loss of appetite, lethargy, dehydration, occasional fever.

🧪 Diagnostic Workflow

1. History & exam: chronic GI signs, appetite, weight trends.
2. Bloodwork: CBC, full Biochem, T4, FeLV/FIV screening, cPLI (pancreatitis marker).
3. Faecal testing: multiple samples for parasites; PCR for Tritrichomonas.
4. Abdominal ultrasound: assess bowel wall thickening, lymph nodes, pancreas.
5. Endoscopy with biopsy: visual and minimally invasive.
6. Full-thickness biopsy: gold standard; obtained via laparotomy/laparoscopy under anesthesia.

💊 Treatment & Management

1. Dietary Therapy

• ➡️ Novel or hydrolyzed protein diets: minimize allergen exposure.
• ➡️ High-fiber or low-fat formulations: aid large intestinal or systemic cases.
• ➡️ Probiotics or prebiotics: promote gut balance.

2. Medications

• Corticosteroids: prednisolone 1–2 mg/kg/day, taper to lowest effective dose.
• Immunomodulators: budesonide, chlorambucil, cyclosporine for refractory cases.
• Antibiotics: metronidazole or tylosin for bacterial overgrowth or colitis.
• Anti-vomiting agents: maropitant, ondansetron.
• Prokinetics: cisapride/metoclopramide if motility impairment.

3. Treat Underlying Conditions

• Treat parasites, Giardia, or Tritrichomonas based on testing.
• Manage pancreatitis/cholangitis (“triaditis”) with fluids, antibiotics, fluids.
• Assess and address stress, food changes, comorbidities.

🥗 Nutrition & Diet Plan

• Slow diet transition: over 7–14 days to reduce upset.
• Consistent feeding schedule: 2–3 meals/day.
• Hydration strategies: wet food, water fountains.
• Consider supplementing: omega-3s, antioxidants; Woopf & Purrz offer suitable options.

🏠 Home Care & Monitoring

• 📓 Keep symptom diary: appetite, vomiting, stool quality, weight.
• 📉 Weigh your cat weekly initially.
• 🔁 Recheck every 4–6 weeks during stabilization; then every 3–6 months.
• 📱 Use Ask A Vet for telehealth symptom monitoring and diet tweaks.
• ⚠️ Watch for dehydration, blood or mucus in stool, worsening signs.

🤝 Role of Ask A Vet, Woopf & Purrz

Ask A Vet provides:

• 🔎 Symptom review and diet evaluation through telehealth sessions.
• 💬 Advice on steroid tapering, adding immunosuppressives, antibiotic choices.
• 📆 Support for ongoing monitoring and home testing.

Woopf & Purrz offer therapeutic-quality GI support diets—novel proteins, hydrolyzed proteins, probiotics—to restore gut balance and reduce inflammation.

📆 Prognosis & Follow-Up

• With early, aggressive therapy, up to 70–80% of cats achieve remission.
• Refractory or IBD linked with lymphoma may require advanced therapies.
• Long-term monitoring crucial; recurrences may need therapy adjustments.
• Most cats maintain good quality of life with tailored care.

✅ Key Takeaways

• IBD = chronic GI inflammation with variable signs depending on location.
• Diagnosis requires testing, imaging, and ideally biopsy for confirmation.
• Treatment combines diet, medication, and managing underlying issues.
• Home tracking and telehealth support ensure consistency and adjustment.
• With care, many cats thrive with controlled IBD in 2025 and beyond.

📞 Final Thoughts

Inflammatory Bowel Disease can challenge your cat—but with clear diagnosis, targeted therapy, and expert support from Ask A Vet and nutrition from Woopf & Purrz, your feline companion can live comfortably and contentedly. 😊🍃

Questions about diet picks, therapy adjustments, or monitoring techniques? Visit AskAVet.com and download the Ask A Vet app for ongoing support!