Metoclopramide for Rabbits: Vet Guide 2025 🐇💊
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Metoclopramide for Rabbits: Vet Guide 2025 🐇💊
By Dr Duncan Houston BVSc
💡 What is Metoclopramide?
Metoclopramide is a prescription medication that acts as a prokinetic and antiemetic. In rabbits, it’s primarily used to treat gastrointestinal (GI) stasis—a condition where gut movement slows or stops. It works by enhancing intestinal motility and blocking dopamine receptors that inhibit movement. 🧠💩
🩺 When Is It Used in Rabbits?
Metoclopramide is a key part of the medical protocol for rabbits experiencing:
- GI stasis or ileus (sluggish gut activity) 🐢
- Post-surgical recovery to stimulate the gut 🔁
- Hairball (trichobezoar) passage issues 🐇🧶
- Some nausea-related conditions 🤢
However, it’s not suitable if a mechanical obstruction is suspected. Imaging (e.g., x-ray or ultrasound) is often recommended before starting treatment. 🛑📸
💊 Safe Dosage Guidelines
| Route | Dosage | Frequency |
|---|---|---|
| Oral (PO) | 0.5 mg/kg | Every 6–8 hours |
| Subcutaneous (SC) | 0.5 mg/kg | Every 6–8 hours |
| Injectable (IM/IV) | 0.2–1.0 mg/kg | Every 8–12 hours |
📌 Always follow your rabbit-savvy vet’s instructions, and give metoclopramide 30 minutes before feeding for optimal results. 🕧🍽️
🚫 Contraindications: When NOT to Use
- Suspected or confirmed GI obstruction or perforation ❌
- History of seizures or epilepsy ⚡
- Kidney disease (use cautiously with monitoring) 🩸
- Known hypersensitivity to the medication ❗
Metoclopramide stimulates intestinal movement—if there’s a blockage, it can make things worse. Always rule out obstruction first. 🔍🧪
⚠️ Potential Side Effects
Though usually well-tolerated in rabbits, some may experience:
- Restlessness or agitation 🐇😬
- Involuntary muscle twitches or tremors 🤯
- Loss of appetite or diarrhea 🚽
- Rarely, seizures (if predisposed) ⚡
If any of these occur, stop the medication and call your vet immediately. ☎️👨⚕️
🛠️ How to Administer
- Oral liquid: Use a syringe for precise dosing. Sweeten with flavor if bitter. 🥄💧
- Subcutaneous injection: Often used in clinics or under vet guidance at home. 💉🐰
- Timing: Give 30 minutes before meals or feeding support. ⏰🍴
Combine with other supportive care for best results. 💪
🔗 Metoclopramide in GI Stasis Protocol
GI stasis is rarely treated with just one medication. A complete plan usually includes:
- Metoclopramide 💊
- Cisapride (colon-specific motility) ➕
- Fluids (SC or IV) 💧
- Analgesics (meloxicam, buprenorphine) 💢
- Syringe-feeding (e.g., Critical Care) 🥄
- Probiotics or simethicone (gas relief) 🍃
✅ Monitoring Recovery
- Normal-sized, round droppings resume 💩
- Appetite returns (hay > pellets) 🐇🌿
- Increased activity and grooming 💃🧼
- No signs of bloating, straining, or lethargy 🚫😵
If no improvement is seen after 24–48 hours, return to the vet immediately. 🏥🚨
📋 Quick Reference Summary
| Use | GI stasis, gut motility stimulation, nausea |
|---|---|
| Typical Dose | 0.5 mg/kg every 6–8 hrs (oral or SC) |
| Avoid If | Obstruction, epilepsy, kidney disease |
| Side Effects | Tremors, agitation, diarrhea |
| Pair With | Cisapride, fluids, pain meds, Critical Care |
🧠 Vet Tips for 2025
- Metoclopramide works best when gut sounds are present 🩺🎧
- Use in conjunction with rehydration and pain relief 💦🛏️
- Document food intake and poop output during treatment 📊
- Don’t delay vet care—stasis is urgent! 🆘
- Recheck with your vet if treatment continues beyond 5 days without full resolution 🗓️
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- Ask A Vet: Get 24/7 live vet consultations for GI issues, medication questions, and recovery advice.
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