The Vet’s 2025 Guide to Sentinel® 🐕💊: Parasite Protection for Dogs by Dr Duncan Houston BVSc

Hi, I’m Dr Duncan Houston BVSc—your trusted vet and pet care advocate. Today, I’m diving into **Sentinel®**: the monthly tablet that keeps dogs safe from a host of unwanted parasites 🐶🔒.

🔬 What Is Sentinel®?

Sentinel® combines two powerful ingredients—milbemycin oxime and lufenuron—to fight parasites **inside and out**:

• 🦠 Milbemycin oxime: Prevents heartworm & treats intestinal worms (roundworms, hookworms, whipworms)
• 🐜 Lufenuron: Halts flea development by preventing eggs from hatching

🌐 Sentinel vs. Sentinel Spectrum®

There are two Sentinel versions:

• Sentinel® Flavor Tabs®: Milbemycin + lufenuron—protects against heartworms, intestinal worms, and flea eggs :contentReference[oaicite:4]{index=4}
• Sentinel Spectrum® Chews: Adds praziquantel to also combat tapeworms—covering **six** types of parasites :contentReference[oaicite:5]{index=5}

👤 Who Can Take It?

Safe for puppies (at least 4 weeks old & 2 lb+) and adult dogs. Spectrum® is approved from 6 weeks, too :contentReference[oaicite:6]{index=6}.

🛡️ What It Protects Against:

• 💓 Heartworm disease (Dirofilaria immitis)
• 🐛 Hookworms (Ancylostoma caninum)
• 🔄 Roundworms (Toxocara canis / leonina)
• 🥇 Whipworms (Trichuris vulpis)
• 🐜 Flea eggs (sterilization by lufenuron)
• 🪱 (Spectrum® only) Tapeworms (Dipylidium, etc.)

📅 Administration & Dosing

🗓️ Frequency

Once a month, ideally with food to enhance absorption 🍽️. If missed, give ASAP and restart monthly schedule—but don’t double-dose.

📏 Tablet Colors by Weight

Color-coded for convenience:

• Brown: 2–10 lb (milb/o 2.3 mg + lu/ 46 mg)
• Green: 11–25 lb (5.75 mg +115 mg)
• Yellow: 26–50 lb (11.5 mg +230 mg)
• White: 51–100 lb (23 mg +460 mg)

✅ Pre-treatment Steps

• 🐕 Heartworm test recommended prior to starting
• 🧪 Treat any active heartworm infections first—failure to do so can trigger serious reactions

⚠️ Possible Side Effects

Generally tolerable, but watch for:

• 🤢 Digestive upset (vomiting, diarrhea, appetite loss)
• 😴 Lethargy, weakness, drooling
• 🧠 Neurologic signs (incoordination, seizures)—rare

📌 Key Safety Notes

• Keep out of children’s reach
• Avoid overdose—follow guidelines carefully
• Concurrent adulticide (like Capstar®) may be needed for adult fleas :contentReference[oaicite:12]{index=12}
• Don’t exceed monthly use—puppy overdose with milbemycin in exorbitant doses was tolerated but not recommended :contentReference[oaicite:13]{index=13}

📋 Monitoring & Follow‑Up

With consistent use: retest heartworm annually, check for side effects, and ensure full monthly use for at least **six months** in mosquito season :contentReference[oaicite:14]{index=14}.

🏠 Home Support Tips

Boost pet health with:

• 🐩 Daily grooming and visual checks for fleas/ticks
• 📱 Use the Ask A Vet app to track dosing & symptoms
• 🎯 Mental & physical enrichment via Woopf interactive games
• 🌿 Calm mealtime routines with Purrz supplements

🌟 When to Switch or Add Products

• 🐾 For tapeworm protection, use Sentinel Spectrum®
• ☔ In high-flea environments, add an adulticide like Capstar®
• 💉 Other heartworm preventives (like Heartgard®) offer similar efficacy; choice depends on your pet’s needs

🎯 Summary from Dr. Duncan

Sentinel® is a smart, once-a-month defense that guards your dog against heartworms, intestinal worms, and halts flea eggs—perfect for year-round protection 🛡️🐶. For broader coverage, choose Sentinel Spectrum®.

Getting the **color-coded chews**, giving them with food, testing for heartworms beforehand, and using our partner tools—**Ask A Vet**, **Woopf**, and **Purrz**—makes parasite prevention easy, effective and stress-free.

Have questions or need support? Visit AskAVet.com or download the Ask A Vet app today 🐾📱.

With care and clarity,
Dr Duncan Houston BVSc 🩺🐕