Trichomoniasis in Cats: A Vet’s 2025 Guide to Diagnosis, Treatment & Home Support 🐱

Hello! I’m Dr. Duncan Houston BVSc, veterinarian and founder of Ask A Vet. In this comprehensive 2025 guide, we cover **trichomoniasis**—an infectious cause of chronic large-bowel diarrhea in cats caused by *Tritrichomonas foetus* (also known as *T. blagburni*). Though often overlooked, it can significantly impact quality of life. This guide helps you spot, diagnose, treat, and support cats with this condition at home—with clarity, compassion, and best-practice insights.

📘 1. What Is Trichomoniasis?

Trichomoniasis is a protozoal infection primarily affecting the colon, causing chronic or recurrent diarrhea with mucus and sometimes blood. Young cats and those in multi-cat environments like shelters and catteries are most at risk :contentReference[oaicite:3]{index=3}.

*T. foetus/blagburni* is a pear-shaped, motile flagellate that thrives in the feline gut and spreads via the fecal-oral route, commonly through shared litter boxes :contentReference[oaicite:4]{index=4}.

👶 2. Who Is at Risk?

• Usually affects young cats under 2 years old :contentReference[oaicite:5]{index=5}.
• Purebreds and cats from catteries or shelters have higher incidence :contentReference[oaicite:6]{index=6}.
• Adult carriers may remain asymptomatic, but can still infect others :contentReference[oaicite:7]{index=7}.

👀 3. Recognizing the Signs

Key clinical signs include:

• Chronic/relapsing large-bowel diarrhea—often malodorous with mucus or fresh blood :contentReference[oaicite:8]{index=8}.
• Tenesmus (straining to defecate), flatulence, fecal dribbling, anal inflammation :contentReference[oaicite:9]{index=9}.
• Cats often maintain normal appetite and body condition, and may not vomit :contentReference[oaicite:10]{index=10}.

🔬 4. Diagnostic Approach

1. Fresh fecal wet mount: microscope exam can catch motile protozoa but has only ~14% sensitivity :contentReference[oaicite:11]{index=11}.
2. Culture tests (e.g., InPouch): sensitivity ~55% :contentReference[oaicite:12]{index=12}.
3. PCR testing: gold standard—most sensitive and specific :contentReference[oaicite:13]{index=13}.
4. Tests should be run on fresh diarrheic samples to optimize detection :contentReference[oaicite:14]{index=14}.
5. Additional tests: fecal checks for other parasites, routine bloodwork to rule out co-infections :contentReference[oaicite:15]{index=15}.

🛠️ 5. Treatment Options

🧪 Ronidazole

• Only antiprotozoal proven effective in cats :contentReference[oaicite:16]{index=16}.
• Typical course: 30–50 mg/kg PO every 12 hrs for 14 days; monitor closely for neurologic side effects :contentReference[oaicite:17]{index=17}.
• Clinical resistance and safety concerns exist; use only after confirmed diagnosis :contentReference[oaicite:18]{index=18}.

💊 Alternative Medications

• Tinidazole has shown some promise, but is used off-label with limited evidence :contentReference[oaicite:19]{index=19}.
• Metronidazole, fenbendazole, or enrofloxacin may temporarily reduce diarrhea but don’t eliminate the parasite :contentReference[oaicite:20]{index=20}.

⏳ Watchful Waiting

• Many cats (up to 88%) resolve symptoms spontaneously within 2 years, though shedding may persist :contentReference[oaicite:21]{index=21}.
• Deciding whether to treat should weigh quality of life, transmission risk, and drug safety :contentReference[oaicite:22]{index=22}.

🧼 6. Hygiene & Environmental Control

• Clean litter box daily; disinfect trays with bleach and UV-dry in sunlight :contentReference[oaicite:23]{index=23}.
• Proper handwashing after litter handling.
• Isolate infected cats during and 2–3 weeks after treatment.
• Maintain cleanliness in multi-cat homes to reduce reinfection risk :contentReference[oaicite:24]{index=24}.

📈 7. Monitoring & Follow-Up

• Re-evaluate stool consistency during and after treatment.
• Repeat PCR or culture 2–3 weeks post-treatment to confirm eradication :contentReference[oaicite:25]{index=25}.
• Track weight, hydration, appetite—use the Ask A Vet app for logs and reminders.

🏡 8. Home Support Strategies

• Offer bland, easily digestible food; increase water intake (wet food, fountains).
• Maintain a calm, stress-free environment—stress can exacerbate symptoms.
• Track stool quality, urgency, accidents via app templates.
• Ensure multiple, clean litter boxes in multi-cat households.

📚 9. Case Example

“Milo,” a 1-year-old shelter cat, had chronic, foul-smelling diarrhea with mucus and occasional blood. PCR confirmed *T. foetus*. He received 14 days of ronidazole and litter-box hygiene. Diarrhea resolved within 5 days, and a negative PCR 3 weeks post-treatment confirmed cure. He remained symptom-free for a year.

🚨 10. When to Contact the Vet Immediately

• Severe diarrhea leading to dehydration
• Weight loss or lethargy despite treatment
• Neurologic signs (due to ronidazole)
• Concurrent illness in kittens, seniors, or immunocompromised cats

✨ 11. Final Thoughts

Feline trichomoniasis, though challenging, is manageable with accurate diagnosis, careful medication, and strict hygiene. Many cats recover fully or live well with mild symptoms. Ask A Vet supports you with treatment reminders, stool tracking tools, litter-box hygiene guidelines, and telehealth follow-up ❤️.

For personalized treatment protocols, home monitoring templates, and ongoing veterinary guidance, visit AskAVet.com or download the Ask A Vet app. We’re here through every scoop and stride of recovery. 🐾