Veterinary Guide to Hematuria in Dogs 2025 💧🐶

By Dr. Duncan Houston BVSc

🩸 What’s Hematuria?

Hematuria is the presence of blood in a dog’s urine, visible as red, pink, orange, brown, or even microscopic traces on urinalysis. It’s always a sign that something is affecting the urinary or reproductive tract 🩸.

🔍 Why It Matters

• Could signal common, treatable issues like UTIs or urinary stones.
• Sometimes points to serious conditions—cancer, kidney disease, trauma, clotting disorders or poisons.
• Puppies and senior dogs are particularly vulnerable.
• Zoonotic risks with certain conditions (like leptospirosis) also matter.

👁️ Clinical Signs & Clues

• Red/pink/orange/brown urine or visible clots
• Straining, painful urination or frequent small urine volumes
• Pale gums (anemia) in severe cases
• Systemic signs—lethargy, fever, vomiting
• Male dogs might show discharge or prostate enlargement; females may bleed due to heat or uterine issues

🧠 Localizing the Bleed

When the blood appears:

• Start of urination: genital or urethral source
• End: bladder origin
• Throughout: possible kidney or ureteral bleeding

🔬 Stepwise Diagnostic Plan

1. History & Physical Exam: timing of bleeding, behaviors, trauma history
2. Urinalysis & Culture: identify blood, infection, crystals, cells
3. Blood Tests: CBC/chemistry to assess anemia, renal health, clotting
4. Imaging: X‑rays/ultrasound to detect stones, tumors, or anatomical deformities
5. Advanced: CT, cystoscopy, urethral catheterization as needed

🧩 Common Causes & Treatments

1. Urinary Tract Infection (UTI)

Most common cause. Treated with antibiotics based on culture for 7–14 days ± anti‑inflammatories.

2. Urinary Stones or Crystals

• Struvite stones: managed via prescription diet; surgery if large or obstructive.
• Calcium oxalate: surgical removal, cystotomy
• Supportive fluids and diet for prevention

3. Bladder or Kidney Tumors

Include transitional cell carcinoma or bladder masses. Diagnosed via imaging + cytology/biopsy. Treated with surgery, chemotherapy, NSAIDs.

4. Prostate Disease (Males)

• Benign enlargement, prostatitis, or cancer: treat with antibiotics, neuter, or surgery.

5. Kidney Disease & Infections

Pyelonephritis is treated with appropriate antibiotics and supportive fluids.

6. Trauma & Clotting Disorders

Treat bladder rupture surgically; address coagulopathies with transfusions, vitamin K, or immunotherapy.

7. Toxins & Systemic Illness

Rodenticides, lilies, hemolytic diseases—treat with decontamination, vitamin K, fluid support.

🏥 Treatment & Supportive Care

• Antibiotics for UTIs and prostatitis
• Pain relief—NSAIDs, opioids if indicated
• Fluids (oral or IV) for hydration and renal perfusion
• Diet changes for stone prevention & urinary tract health
• Surgery or minimally invasive stone/tumor removal
• Blood products or vitamin K for bleeding disorders

🏡 Home Care & Monitoring

• Encourage fresh water & hydration
• Record urine color, volume, and frequency
• Keep litter area clean to reduce infection risk
• Administer meds as directed & complete full courses
• Follow-up: urinalysis & imaging at 2–4 weeks post-treatment

📱 Ask A Vet Integration

• Tele‑consults: Review urinalysis, meds, and home monitoring remotely
• Medication reminders: Scheduled dosing via the app 📲
• Emergency alerts: Notify vet if signs worsen (straining, no urine, pale gums)

🎓 Case Spotlight: “Maggie” the Beagle Puppy

Maggie’s owners noticed pink urine and frequent peeing. Urinalysis showed E. coli UTI; treated with antibiotics, probiotics, and diet. One month later, urinalysis post-treatment was clean, and Maggie is back to playful pup life!

🔚 Final Take‑Home Messages

1. Hematuria is always a sign—never ignore it.
2. Common causes need routine treatment; serious causes require thorough diagnostics.
3. Full diagnostics ensure accurate diagnosis and treatment.
4. Home care & monitoring are critical to recovery.
5. Ask A Vet supports every step—from virtual diagnostics to tailored nutrition and monitoring tools.

Dr Duncan Houston BVSc, Ask A Vet founder. Download the Ask A Vet app for remote urinary care support—helping your pup stay healthy, hydrated, and hematuria-free! 🐶❤️