Guinea Pig Hair Loss & Skin Issues: Vet Guide 2025 – Expert Vet Insights 🐹🩺

— Written by Dr Duncan Houston BVSc, founder of Ask A Vet —

1. Understanding Hair Loss (Alopecia)

“Alopecia” refers to partial or total hair loss in areas where fur normally grows. In guinea pigs, this signals an underlying issue. Hair loss can be either self-induced (e.g., chewing or rubbing) or due to an external cause like parasites, fungal infections, hormonal changes, or nutritional deficiencies :contentReference[oaicite:2]{index=2}.

2. Common Causes of Hair Loss

🐜 A. Parasites

• Mites (e.g., Trixacarus caviae): Often cause severe itching, hair loss, scabs, crusts, and even neurological signs in heavy infestations :contentReference[oaicite:3]{index=3}.
• Lice (Gliricola porcelli): Visible as tiny insects or eggs in fur, causing mild irritation and patchy shedding :contentReference[oaicite:4]{index=4}.

🍄 B. Fungal Infections (Ringworm)

Ringworm typically appears as circular, scaly bald patches—often around the head or rump. It’s zoonotic, so diagnosis and treatment with antifungal creams or oral medications are essential :contentReference[oaicite:5]{index=5}.

✂️ C. Barbering (Self or Cage-mate Chewing)

Behavioral or dominance-related chewing can result in short, uneven fur and sometimes skin inflammation :contentReference[oaicite:6]{index=6}.

⚕️ D. Hormonal Causes (In Intact Females)

Ovarian cysts and pregnancy-associated shedding often lead to symmetrical hair loss on flanks and belly. Spaying usually resolves the condition :contentReference[oaicite:7]{index=7}.

🥦 E. Nutritional Deficiencies (Vitamin C – Scurvy)

Vitamin C deficiency can cause rough coat, scaly or rash-like skin changes, hair loss, lethargy, weight loss, and joint pain—especially in undiagnosed cases :contentReference[oaicite:8]{index=8}.

🏠 F. Environmental & Miscellaneous

• Bedding allergens or poor hygiene: Dirty cages or dusty substrates can irritate skin :contentReference[oaicite:9]{index=9}.
• Bumblefoot or urine scalding: These secondary skin issues can cause localized hair loss :contentReference[oaicite:10]{index=10}.
• Shedding or aging: Known natural thinning behind ears or rump is common and normally harmless :contentReference[oaicite:11]{index=11}.

3. Identifying the Cause

Accurate diagnosis is essential:

• History: Onset timing, cage mates, diet, new environment.
• Physical exam: Check for insects, mites, scabs, inflammation.
• Skin / fur tests: Hair plucks, tape tests, fungal cultures.
• Bloodwork / ultrasound: Used if scurvy or ovarian cysts are suspected.

4. Treatment Strategies

Parasites

• Ivermectin or Selamectin—multiple treatments required for mites or lice :contentReference[oaicite:12]{index=12}.
• Symptomatic care—antihistamines, anti-inflammatories, topical soothing agents.

Ringworm

• Topical antifungals (clotrimazole, miconazole)—or oral treatment in severe cases :contentReference[oaicite:13]{index=13}.
• Disinfection of habitat—wash bedding, toys, and cage surfaces.

Barbering

• Separate aggressive individuals; enrich cage to reduce stress and boredom :contentReference[oaicite:14]{index=14}.
• Ensure balanced diet, high-fiber hay, and low-stress environment.

Hormonal (Ovarian Cysts)

• Spay intact females—prevents recurrence and improves coat :contentReference[oaicite:15]{index=15}.
• Monitor non-surgical cases with ultrasound; hormonal therapy may be suggested.

Vitamin C Deficiency

• Supplement with 10–30 mg/kg/day vitamin C pellets or fresh produce (bell peppers, parsley) :contentReference[oaicite:16]{index=16}.
• Supportive care for joint pain and appetite stimulation.

Dermatitis & Other Conditions

• Improve hygiene: clean bedding, hard-floor living, change dirty habitations.
• Treat secondary infections with appropriate antibiotics.
• Provide foot protection mats for bumblefoot prevention.

5. Preventive Measures

• Quarantine new or rescued guinea pigs for 4 weeks with testing :contentReference[oaicite:17]{index=17}.
• Freeze bedding, hay, and toys to eliminate parasites.
• Maintain clean housing; avoid wire floors and high humidity.
• Ensure daily vitamin C intake via pellets or fresh veg.
• Spay females to prevent cysts and related hair loss :contentReference[oaicite:18]{index=18}.

6. When Veterinary Help Is Needed

• Rapid, widespread hair loss “blitz” across body with itchiness.
• Open wounds, swelling, discharge, or crusting lesions.
• Lethargy, weight loss, lameness, or behavioral changes accompany alopecia.
• Pregnant or intact females with symmetrical flank shedding.
• Home treatments fail to improve within 10–14 days.

7. Role of Ask A Vet

• 📸 Review photos or videos to assess lesions or itchiness remotely.
• Provide medication guidance—dosing antiparasitics, antifungals, or supplements.
• Offer hygiene and environment optimization plans.
• Monitor progress with scheduled follow-ups and care reminders.
• Assist in referrals to local exotic vets when needed.

8. Recovery & Follow-Up

• Healing may take 2–6 weeks depending on cause.
• Gradual fur regrowth possible—monitor coat and skin health post-treatment.
• Aftercare includes cage cleaning, habitat adjustments, and nutritional maintenance.

Conclusion

Hair loss in guinea pigs can stem from various causes—parasitic, fungal, behavioral, hormonal, or nutritional. Early and accurate diagnosis is key to successful treatment. With tailored care, environmental adjustments, and expert support via Ask A Vet, most skin conditions can be resolved and future issues prevented. A healthy, happy coat is within reach 🐾.

Noticed bald patches or irritated skin? Contact your exotic vet and upload photos to Ask A Vet for fast, friendly guidance and a care plan that restores your pet’s coat and comfort 📱

— Dr Duncan Houston BVSc, Ask A Vet