Vet Guide to Clavamox® in 2025 🐾
Hello, I’m Dr Duncan Houston BVSc—founder of Ask A Vet. In this updated 2025 guide, we explore Clavamox®—a trusted combination of amoxicillin and clavulanic acid—used to treat a wide range of bacterial infections in dogs and cats. You’ll learn about its action, when it’s used, proper dosing, potential side effects, and best practices to support your pet's recovery. 🐶🐱
📘 What Is Clavamox®?
Clavamox® combines amoxicillin, a broad-spectrum penicillin antibiotic, with clavulanic acid, which blocks bacterial beta-lactamase enzymes—making the antibiotic more effective against resistant bacteria.
✅ Common Uses in 2025
- Skin and soft tissue infections—wounds, abscesses, cellulitis, superficial/deep pyoderma
- Periodontal (gum) infections in dogs
- Urinary tract infections (UTIs) in dogs and cats
- Respiratory infections—pneumonia, sinusitis, bronchitis
- Periodontal and soft tissue infections in cats; UTIs in cats
📐 Proper Dosing & Administration
Chewable tablets:
- Dogs: 6.25 mg/lb (≈13.75 mg/kg) every 12 hours—usually for 5–7 days for mild infections, extending to 21 days for deep pyoderma, not exceeding 30 days
- Cats: 62.5 mg per cat every 12 hours—typically for 5–7 days (or up to 14 days for UTIs)
Liquid suspension: Shake well, refrigerate, and discard after 10 days.
Give with food to reduce GI upset; store tablets in foil until use.
⏰ Onset & Treatment Duration
Clavamox® starts working within 1–2 hours, though improvements often appear over 2–5 days. Always complete the full course to avoid recurrence or resistance.
⚠️ Side Effects & Allergies
- Gastrointestinal upset: vomiting, diarrhea, decreased appetite, lethargy are the most common
- Allergic reactions: in penicillin-sensitive pets—rash, hives, facial swelling, breathing difficulty—rare but serious
- Contraindications: avoid in rabbits, guinea pigs, and herbivores due to fatal diarrhea risk
🔗 Interactions & Precautions
- Avoid concurrent use with other beta-lactam antibiotics (e.g., cephalosporins) without veterinary guidance
- Inform your vet of supplements or medications as Clavamox® may have interactions
- Human Clavamox/Augmentin should only be used under veterinary direction due to different dosages
🩺 Monitoring & Vet Follow-up
- Expect visible improvement in 2–5 days. Recheck if no response within 3–5 days.
- Monitor GI signs, appetite, behavior daily; report severe reactions.
- Culture & sensitivity testing may be warranted in recurrent or deep infections
⏳ Missed Dose & Overdose
- Missed dose? Administer as soon as noticed, unless it's near the next dose—do not double up
- Overdose signs: vomiting, diarrhea, appetite loss; rare: kidney issues, seizures—seek veterinary care if concerned
🏡 Typical Use Cases
🐶 Dog with Skin Abscess
- 6.25 mg/lb BID for 7 days. Expect improvement in 2–3 days; finish the full course to prevent recurrence.
🐱 Cat with Respiratory Infection
- 62.5 mg BID for 7 days. Monitor for appetite or GI issues; use probiotic if vet approves.
❓ FAQs
Can Clavamox® treat fungal or viral infections?
No—it only treats bacterial infections. Viral or fungal infections need appropriate alternatives.
Why not stop when symptoms improve?
Stopping early risks incomplete infection elimination and antibiotic resistance. Always complete full course.
Is Clavamox® safe during pregnancy or lactation?
Use only under vet supervision due to limited safety data.
Can it be used long‑term?
Usually reserved for short courses (≤30 days). For chronic infections, vet may reassess and consider culture guidance.
📌 Final Takeaways
- Clavamox® is a broad-spectrum, beta-lactamase–protected antibiotic reliable for many common bacterial infections.
- Proper dosing by weight—dogs at 6.25 mg/lb BID, cats at 62.5 mg BID—is critical.
- Give with food, monitor for GI upset or allergies, complete full course.
- Culture before use in recurrent or deep infections; avoid in herbivores or penicillin-allergic pets.
- Consult your vet for dose adjustments, side effects, or lack of improvement.
Considering Clavamox® for your pet’s infection? Download the Ask A Vet app for personalized dosing schedules, treatment reminders, GI tracking, and 24/7 veterinary guidance. Together, we’ll support your pet’s path to recovery. 🐾❤️
This article is general veterinary education and does not diagnose or treat an individual animal. Always confirm medication names, doses and interactions with the veterinarian who knows your pet.
If your animal is struggling to breathe, collapsed, bleeding heavily, seizing, or has eaten something toxic, contact your vet or the nearest emergency clinic now.
Animal Poisons Helpline (AU) 1300 869 738 · Animal Poisons Helpline (NZ) 0800 869 738 · ASPCA Animal Poison Control (US) (888) 426-4435
More from Ask A Vet
For everyday pet care, one scan or tap of the smart pet ID tag opens your pet's free profile on any phone, no app needed; the GPS pet tracker logs live location and activity trends; and the Ask A Vet app keeps your pet's records and routines together.
QR Code Dog & Cat ID Tag with NFC, HangingView ID TagThe ASK A VET™ Smart ID Tag is a QR scan or NFC tap on any phone, no app needed, with a free profile you can update anytime.
Dog & Cat GPS Tracker for Their CollarView trackerThe ASK A VET™ Tracker logs live location and activity trends, so a change in routine never goes unnoticed.
- Talk to a Vet Online: The Ask A Vet AppExplore the app
Ask questions, speak with vets, and keep your pet's records and routines together with Ask A Vet.

Ask A Vet articles are written by Dr Duncan Houston BVSc, a practising veterinarian, unless another author is named in the byline.



