Veterinary 2025 Guide: Osurnia® Otic Gel for Canine Otitis Externa 🐶🩺
Hello, I’m Dr Duncan Houston BVSc. This 2025 guide covers Osurnia® Otic Gel—an innovative, long-acting combination therapy for canine otitis externa. We'll explore its formulation and mechanism, dosing protocol, safety concerns (including hearing and eye risks), contraindications, monitoring, and client education supported by Ask A Vet tools 😊.
🔎 1. What Is Osurnia®?
Osurnia® combines:
- Florfenicol – broad-spectrum antibiotic targeting Staph. pseudintermedius.
- Terbinafine – antifungal agent effective against Malassezia pachydermatis.
- Betamethasone acetate – corticosteroid to reduce inflammation and itching.
FDA-approved for treating acute and recurrent otitis externa in dogs.
💧 2. Dosing Protocol
- Two in-clinic doses, 7 days apart. Each dose: 1 tube (1 mL) per affected ear.
- No ear cleaning for 45 days after the first dose; gel adheres and treats throughout.
- Improvement most often occurs within 30–45 days post-first dose.
⚠️ 3. Safety & Adverse Events
- Common clinical reactions: vomiting, transient hearing loss, elevated liver enzymes, ear irritation, head shaking.
- Rare serious effects: ataxia, head tilt, nystagmus, corneal ulcers, facial paralysis, keratoconjunctivitis sicca, and ear drum rupture.
- Eye exposure risk: splashes from shaking can cause corneal ulcers and eye irritation in dogs and humans—wear eye protection and restrain the dog during application.
🚫 4. Contraindications & Precautions
- Do not use if the eardrum is perforated.
- Avoid in dogs with hypersensitivity to any active ingredients or excipients.
- Not for use in pregnant, breeding, or lactating dogs; safety not established.
- Use carefully in dogs with liver or kidney disease due to systemic absorption.
🩺 5. Monitoring & Follow‑Up
- Check for hearing changes, head tilt, ear pain, discharge, or systemic signs of illness daily.
- If severe signs appear, reevaluate ear canal status—conduct otoscopic exam and consider culturing.
- Schedule a recheck 7 days after the first dose (for the second dose) and again at 45 days to confirm resolution.
📝 6. Client Education & Home Support
- Explain in-clinic dosing, absence of ear cleaning for 45 days, and expected treatment timeline.
- Demonstrate safe handling: wear gloves, use eye protection, and secure the dog to prevent splatter.
- Clarify common vs. serious side effects—including when to seek immediate veterinary care.
- Recommend using Ask A Vet app for treatment reminders, symptom logging, secure photo uploads, and direct vet messaging 😊.
📌 7. 2025 Vet Takeaways
- Osurnia® offers a convenient dual-dose gel therapy combining antibiotic, antifungal, and steroid action.
- Avoid ear cleaning to maintain gel contact and maximize effectiveness.
- Watch for hearing loss, eye exposure, and rare neurologic or ocular adverse effects.
- Restraint, gloves, and eye protection are essential during application.
- Digital owner support via Ask A Vet can improve adherence and outcomes 😊.
At Ask A Vet, we provide treatment schedules, adverse-effect alerts, and 24/7 veterinary messaging tools to help clients manage ear infections effectively. Encourage owners to download our app for seamless care ❤️
This article is general veterinary education and does not diagnose or treat an individual animal. Always confirm medication names, doses and interactions with the veterinarian who knows your pet.
If your animal is struggling to breathe, collapsed, bleeding heavily, seizing, or has eaten something toxic, contact your vet or the nearest emergency clinic now.
Animal Poisons Helpline (AU) 1300 869 738 · Animal Poisons Helpline (NZ) 0800 869 738 · ASPCA Animal Poison Control (US) (888) 426-4435
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Ask A Vet articles are written by Dr Duncan Houston BVSc, a practising veterinarian, unless another author is named in the byline.




