IV Drug Compatibility Checker for Dogs and Cats
Which injectable drugs and fluids can share one IV line, catheter lumen or bag in a hospitalised dog or cat. Tick the drugs, choose the carrier fluid, map them onto the catheters you have placed, and every pair is graded from published Y-site and admixture data, with a suggested split into the fewest lines.
Choose the patient, the carrier fluid and the drugs
Choose the species and the carrier fluid running through the line, then search and tick every drug the patient is receiving.
Checked against every drug; each line can override it below.
162 injectables and fluids; type a name, brand or class, then press Enter to add the first match.
Selected drugs 0
How the selected drugs grade together
The summary shows how many pairs are compatible, caution, incompatible or without data, plus a suggested split into the fewest lines.
Map the drugs onto the catheters you have placed
Mark the limb each line goes into, then print or download the line map, or copy the notes into the record.
Body map (dorsal view, head at top; animal's left is on the left). Click a limb, the neck or the ear to add a line there.
The kennel sheet has the body map with numbered lines, what runs through each, compatibility status, safety notes and sign-off boxes. Print it, save it as a PDF or PNG image for the record or to send to a colleague, or copy the plan as text to paste into the medical record. Files are made in your browser; nothing is uploaded.
Notes for the medical record: preview and edit before copying
Each line (or lumen of a multi-lumen catheter) is checked on its own: every drug on the line against every other drug on that line and against the line's carrier fluid. Lumens of one central catheter count as separate lines. Drugs marked "flush and give separately" can still be given as boluses through a line if you flush before and after, provided they are not marked incompatible with what is running.
Every pair, graded and sourced
Filter the list by grade to read only the pairs you need to act on.
The whole selection at a glance
Every selected drug against every other: read across a row and down a column for that pair’s grade.
Professional use only. Compatibility data are guidance at usual concentrations and do not account for your specific concentrations, additives, or contact time. Always confirm against a current injectable-drugs reference and inspect the line. This tool does not replace veterinary clinical judgement or pharmacy advice.
About the IV drug compatibility checker
Hospitalised dogs and cats often need several intravenous drugs at once: a fluid plan, an analgesic infusion such as MLK or FLK, potassium supplementation, antibiotics, antiemetics and sometimes vasopressors or insulin. Most patients only have one or two catheters. This veterinary IV compatibility checker tells you which drugs can safely share a line or Y-site, which must never meet, and how to split the rest across the catheters you have. It covers 162 injectables and fluids used in small-animal emergency and critical care, graded from published Y-site and admixture data, and works like a searchable veterinary IV compatibility chart that also plans your lines.
Last reviewed: August 2026. Data are re-checked against the source charts and labels when they are revised; report an error via the contact page.
How to use it
Choose the species and the carrier fluid running through the line, then search and tick every drug the patient is receiving. The summary shows how many pairs are compatible, caution, incompatible or without data, plus a suggested split into the fewest lines. In the lines and catheters step, add each catheter you have placed (left or right cephalic, medial or lateral saphenous, jugular single or multi-lumen, intraosseous), assign a carrier and the drugs running through it, and the tool checks each line as its own system. Switch to same bag or syringe mode when you are mixing drugs in one container, which is stricter than a brief Y-site meeting. Print the plan for the kennel sheet, download it as a PDF or PNG image, or copy the notes into the medical record.
What Y-site compatibility means (and what it does not)
Y-site compatibility means two solutions can meet briefly in the tubing (at a Y-port or three-way tap) close to the patient without forming a precipitate, haze, gas or colour change, at usual concentrations. It says nothing about long contact. Admixture or same-bag compatibility means the drugs stay physically and chemically stable together for hours in one bag or syringe, which needs stability data. Incompatible means a visible change or a known loss of potency has been reported. Physical compatibility (what you can see) is not the same as chemical compatibility (potency), which is why aminoglycosides plus penicillins can look clear and still inactivate each other. A lumen is one channel of a multi-lumen central catheter; the channels do not meet until the catheter tip, so each lumen is treated as its own line. A CRI is a constant rate infusion.
Incompatibilities every vet and nurse should know
Ceftriaxone must never meet calcium, so it cannot run in Lactated Ringer's or Hartmann's or with calcium gluconate: use 0.9% saline and a separate line. Sodium bicarbonate is strongly alkaline and inactivates adrenaline, noradrenaline, dopamine and dobutamine, and precipitates with calcium. Calcium and phosphate precipitate together, so potassium phosphate does not belong in a calcium-containing bag. Aminoglycosides (gentamicin, amikacin) and beta-lactams (ampicillin, cefazolin, ceftriaxone) inactivate each other when mixed, and heparin inactivates aminoglycosides. Furosemide is alkaline and precipitates with acidic drugs such as midazolam, dobutamine, ondansetron and metoclopramide. Diazepam precipitates on dilution and adsorbs to PVC, so it goes in slowly and alone. Propofol, Intralipid and parenteral nutrition are lipid emulsions that crack when other drugs meet them. Blood products run only with 0.9% saline: calcium in Hartmann's clots the line and dextrose haemolyses red cells. Glucagon precipitates in saline and needs 5% dextrose. Amphotericin B is dextrose-only. Trimethoprim-sulfa IV precipitates in saline and is given alone in dextrose. Proton pump inhibitors (pantoprazole, omeprazole, esomeprazole) are alkaline and precipitate with midazolam and many acidic drugs.
Common CRI combinations in dogs and cats, and what they run with
MLK (morphine, lidocaine, ketamine) and FLK (fentanyl, lidocaine, ketamine) are routinely made up in one bag of 0.9% saline or Hartmann's for dogs; in cats, MK or FK without lidocaine is usual. These bags are Y-site compatible with most catecholamine CRIs, potassium chloride, metoclopramide and dexmedetomidine, but not with furosemide, sodium bicarbonate or diazepam. Potassium chloride is added to any crystalloid bag (never faster than 0.5 mEq/kg/hour); potassium phosphate goes in saline or dextrose, not Hartmann's. A regular insulin CRI is made in 0.9% saline (prime the line first because insulin adsorbs to plastic) and runs happily beside potassium and dextrose supplementation. Metoclopramide can go straight into the maintenance bag (protect from light) but must not meet furosemide, penicillins or a PPI in the line. Dexmedetomidine CRI is diluted in saline or Hartmann's and is labelled compatible with fentanyl, morphine, midazolam, ketamine, butorphanol, atropine, glycopyrrolate and phenylephrine. Dopamine, dobutamine and adrenaline run in saline or dextrose and share a line with opioids, midazolam, ketamine and lidocaine, but never with bicarbonate; noradrenaline is best in dextrose-containing fluid. Furosemide CRI belongs in saline or Hartmann's, not dextrose. Sodium nitroprusside and amiodarone are dextrose-only. Use the CRI calculator for the doses.
What can go in, or run with, each fluid bag
Generated from the same data as the checker. "Can run with" covers Y-site co-infusion and, where the note says so, adding to the bag; always check the pair in the tool for the conditions.
0.9% sodium chloride
0.9% sodium chloride (normal saline) is the most forgiving carrier: it contains no calcium, no dextrose and no buffer, so it is the default line for blood products, ceftriaxone, phosphate and most CRIs.
Can run with or be added to it (132): Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Aminocaproic acid, Aminophylline, Amoxicillin-clavulanate, Ampicillin, Ampicillin-sulbactam, Antivenom, Atracurium, Atropine, B complex, Blood products, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carboplatin, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Cisplatin, Clindamycin, Cosyntropin (ACTH), Cyclophosphamide, Cyclosporine, D5W, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxorubicin, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glycopyrrolate, Heparin, HES colloid, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Imipenem-cilastatin, Insulin, Iodinated contrast, K phosphate, KCl, Ketamine, Levetiracetam, Lidocaine, Lorazepam, LRS / Hartmann's, Mannitol, Marbofloxacin, Meropenem, Methadone, Methocarbamol, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Piperacillin-tazobactam, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Thiamine, Thiopental, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vinblastine, Vincristine.
Never (3): Amiodarone, Amphotericin B, Glucagon.
Caution or better fluid available (21): Amino acids, Apomorphine, Atipamezole, Carprofen, Diazepam, Etomidate, hIVIG, Hypertonic saline, Intralipid 20%, Ketoprofen, Maropitant, Meloxicam, Methylene blue, Nitroglycerin, Nitroprusside, Oxyglobin, Parenteral nutrition, Pimobendan inj, Tetanus antitoxin, Tiletamine-zolazepam, Vitamin K1.
Lactated Ringer's / Hartmann's
Lactated Ringer's / Hartmann's contains calcium, which is what causes most of its incompatibilities (ceftriaxone, phosphate, bicarbonate, pamidronate, blood products) and is why some CRIs are made up in saline instead.
Can run with or be added to it (85): 0.9% NaCl, Adrenaline, Alfaxalone, Amikacin, Aminocaproic acid, Aminophylline, Amoxicillin-clavulanate, Ampicillin, Ampicillin-sulbactam, Atracurium, Atropine, B complex, Buprenorphine, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Cefuroxime, Cimetidine, Clindamycin, D5W, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Diltiazem, Diphenhydramine, Dobutamine, Dolasetron, Dopamine, Doxycycline, Erythromycin, Esmolol, Esomeprazole, Famotidine, Fentanyl, Fluconazole, Flumazenil, Furosemide, Gelatin colloid, Gentamicin, Heparin, HES colloid, Hydrocortisone, Hydromorphone, Insulin, KCl, Ketamine, Labetalol, Levetiracetam, Lidocaine, Meropenem, Methylprednisolone SS, Metoclopramide, MgSO4, Midazolam, Milrinone, Morphine, NAC, Nitroglycerin, Noradrenaline, Omeprazole, Ondansetron, Oxytocin, Pantoprazole, Paracetamol IV, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Piperacillin-tazobactam, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Thiamine, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vecuronium.
Never (12): Amiodarone, Amphotericin B, Blood products, Ceftriaxone, Glucagon, hIVIG, K phosphate, Na phosphate, Nitroprusside, Oxyglobin, Pamidronate, Tetanus antitoxin.
Caution or better fluid available (58): Acepromazine, Albumin, Amino acids, Antivenom, Apomorphine, Atipamezole, Butorphanol, Carboplatin, Carprofen, Chloramphenicol, Chlorphenamine, Chlorpromazine, Ciprofloxacin, Cisatracurium, Cisplatin, Cyclophosphamide, Cyclosporine, Desmopressin, Diazepam, Digoxin, Dipyrone, Doxorubicin, Enrofloxacin, Ephedrine, Ethanol, Etomidate, Fomepizole, Glycopyrrolate, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Intralipid 20%, Iodinated contrast, Ketoprofen, Lorazepam, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Methadone, Methocarbamol, Methylene blue, Metronidazole, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Oxymorphone, Parenteral nutrition, Pimobendan inj, Pralidoxime, Terbutaline, Thiopental, Tiletamine-zolazepam, Vasopressin, Vinblastine, Vincristine, Vitamin K1.
Plasma-Lyte 148 / Normosol-R
Plasma-Lyte 148 / Normosol-R is calcium-free but contains magnesium and acetate; it avoids the calcium problems of Hartmann's, though fewer drugs have published data with it.
Can run with or be added to it (64): Adrenaline, Aminocaproic acid, Aminophylline, Atropine, B complex, Ca chloride, Ca gluconate, Cefazolin, Ceftazidime, Ceftriaxone, Cimetidine, Ciprofloxacin, Clindamycin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Diltiazem, Diphenhydramine, Dobutamine, Dopamine, Doxycycline, Esmolol, Famotidine, Fentanyl, Fluconazole, Flumazenil, Furosemide, Gelatin colloid, Gentamicin, Glycopyrrolate, Heparin, HES colloid, Hydrocortisone, K phosphate, KCl, Ketamine, Labetalol, Levetiracetam, Lidocaine, Meropenem, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Milrinone, Morphine, Na phosphate, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Paracetamol IV, Phenylephrine, Piperacillin-tazobactam, Prednisolone SS, Procainamide, Remifentanil, Rocuronium, Thiamine, Tranexamic acid, Vancomycin, Vecuronium.
Never (9): Amiodarone, Amphotericin B, Cyclosporine, Glucagon, hIVIG, Oxyglobin, Pamidronate, Propofol, Tetanus antitoxin.
Caution or better fluid available (61): Acepromazine, Albumin, Alfaxalone, Amino acids, Antivenom, Apomorphine, Atipamezole, Atracurium, Blood products, Buprenorphine, Butorphanol, Carboplatin, Carprofen, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cisatracurium, Cisplatin, Cyclophosphamide, Desmopressin, Diazepam, Dipyrone, Doxorubicin, Enrofloxacin, Ephedrine, Erythromycin, Esomeprazole, Ethanol, Etomidate, Fomepizole, Hydralazine, Hydromorphone, Hypertonic saline, Insulin, Intralipid 20%, Iodinated contrast, Ketoprofen, Lorazepam, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Methadone, Methocarbamol, Methylene blue, Midazolam, NAC, Naloxone, Neostigmine, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Pralidoxime, Terbutaline, Tiletamine-zolazepam, Trimethoprim-sulfa, Vasopressin, Vinblastine, Vincristine, Vitamin K1.
5% dextrose in water
5% dextrose in water is the diluent of choice for a few drugs that precipitate in saline (glucagon, amphotericin B, trimethoprim-sulfa) and is acidic, which is why some alkaline drugs (furosemide) degrade in it. Never run blood with it.
Can run with or be added to it (127): 0.9% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amphotericin B, Atracurium, Atropine, B complex, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carboplatin, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cyclophosphamide, Cyclosporine, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxorubicin, Doxycycline, Enrofloxacin, Ephedrine, Esmolol, Esomeprazole, Ethanol, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Imipenem-cilastatin, Insulin, K phosphate, KCl, Ketamine, Labetalol, Levetiracetam, Lidocaine, Lorazepam, LRS / Hartmann's, Mannitol, Marbofloxacin, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Pamidronate, Pantoprazole, Paracetamol IV, Pentobarbital, Phenobarbital, Phenylephrine, Piperacillin-tazobactam, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Thiamine, Thiopental, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vinblastine, Vincristine.
Never (2): Amoxicillin-clavulanate, Blood products.
Caution or better fluid available (27): Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Carprofen, Cisplatin, Desmopressin, Diazepam, Erythromycin, Etomidate, hIVIG, Hypertonic saline, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Meloxicam, Oxyglobin, Oxytocin, Parenteral nutrition, Penicillin G, Pimobendan inj, Pralidoxime, Tetanus antitoxin, Tiletamine-zolazepam, Vitamin K1.
How to give a drug that is not compatible with what is running
Use another catheter or a separate lumen if you have one. If not: pause the infusion, flush the line with 3 to 10 mL of 0.9% saline (or another fluid compatible with both drugs) at the port nearest the patient, give the drug at the labelled rate, flush again with the same volume, then restart the infusion. Never flush a line running a vasopressor or insulin faster than the pump was delivering, and do not bolus through a line carrying blood, lipid or parenteral nutrition. Label every line with its contents, use a pump for every CRI, and look at the tubing below the Y-site whenever a new drug is connected.
Drugs that always need a dedicated IV line
The planner always gives these their own catheter or lumen, whatever else the patient is receiving:
- Blood products (whole blood, pRBC, plasma, platelets, cryoprecipitate): Only 0.9% sodium chloride may run with them: calcium in Hartmann's or LRS can overcome the citrate anticoagulant and clot the line, dextrose haemolyses red cells, and no drug should be added to or Y-sited into a transfusion line.
- Intralipid 20% (lipid emulsion): A lipid emulsion: many drugs crack it and cracked emulsion is an embolic risk. Own line for lipid rescue; the same applies to propofol infusions.
- Parenteral nutrition: A complex admixture of amino acids, dextrose, lipid and electrolytes; only drugs your PN reference lists may share the lumen. Dedicated lumen of a central line.
- Propofol: A lipid emulsion. Boluses go through the injection port of a running crystalloid with a flush; a CRI runs from its own syringe pump line, and it is not added to bags or mixed with other drugs.
- Amphotericin B: Precipitates in saline and electrolyte solutions: dilute in 5% dextrose only and give alone.
- Trimethoprim-sulfamethoxazole IV: Precipitates readily in saline and at high concentration: dilute in 5% dextrose, infuse slowly, give alone and flush.
- Human intravenous immunoglobulin (hIVIG): A biological given over hours: dedicated line, only the labelled diluent, no other drugs, watch for reactions.
- Oxyglobin (haemoglobin glutamer): Given through a dedicated line with a standard giving set; do not add drugs or run other fluids through it.
- Tetanus antitoxin and antivenom: Biologicals: give slowly by themselves and watch for anaphylaxis; a separate line or a paused, flushed line.
- Amino acid solutions: A component of parenteral nutrition: alone, or only what your PN reference lists.
- Iodinated contrast: Not mixed with other drugs: flush with 0.9% saline before and after, check hydration and renal values first.
- Chemotherapy: vincristine, vinblastine, doxorubicin, carboplatin, cisplatin, cyclophosphamide: A dedicated, freshly placed first-stick catheter with its own giving set, never Y-sited with other drugs or piggybacked onto the fluid line, saline flush before and after, closed-system cytotoxic handling. Vinca alkaloids and doxorubicin are vesicants; cisplatin is saline-only and never given to cats.
Two more are given alone rather than on a dedicated catheter: diazepam precipitates on dilution and adsorbs to PVC, so it goes in slowly, neat, with a flush; maropitant has no published compatibility data and the product information says not to mix it, so it is given slowly on its own with a flush before and after.
Same-syringe premedication and sedation combinations
Which premedication, sedation and induction drugs can be drawn up in the same syringe or run together, from product labels, veterinary practice references and syringe-driver compatibility data (physically compatible at usual doses; the checker note names the source for each pair). Same-syringe means drawn up for immediate use, not stored.
- Dexmedetomidine with Atropine, Buprenorphine, Butorphanol, Fentanyl, Glycopyrrolate, Ketamine, Methadone, Midazolam, Morphine, Nalbuphine, Tiletamine-zolazepam.
- Butorphanol with Acepromazine, Dexmedetomidine, Glycopyrrolate, Ketamine, Midazolam, Tiletamine-zolazepam.
- Buprenorphine with Acepromazine, Dexmedetomidine, Glycopyrrolate, Midazolam.
- Methadone with Acepromazine, Dexamethasone SP, Dexmedetomidine, Ketamine, Lidocaine, Metoclopramide, Midazolam.
- Morphine with Acepromazine, Atropine, Dexamethasone SP, Dexmedetomidine, Glycopyrrolate, Ketamine, Lidocaine, Metoclopramide, Midazolam, Ondansetron.
- Fentanyl with Dexmedetomidine, Glycopyrrolate, Ketamine, Lidocaine, Midazolam.
- Hydromorphone with Glycopyrrolate.
- Oxymorphone with Acepromazine, Glycopyrrolate, Midazolam.
- Nalbuphine with Dexmedetomidine, Glycopyrrolate.
- Ketamine with Acepromazine, Atropine, Butorphanol, Dexmedetomidine, Fentanyl, Lidocaine, Methadone, Midazolam, Morphine, Tiletamine-zolazepam.
- Tiletamine-zolazepam with Butorphanol, Dexmedetomidine, Ketamine.
- Midazolam with Atropine, Buprenorphine, Butorphanol, Dexmedetomidine, Fentanyl, Ketamine, Methadone, Morphine, Oxymorphone.
- Acepromazine with Buprenorphine, Butorphanol, Ketamine, Methadone, Morphine, Oxymorphone.
- Glycopyrrolate with Atropine, Buprenorphine, Butorphanol, Dexmedetomidine, Diphenhydramine, Fentanyl, Hydromorphone, Lidocaine, Morphine, Nalbuphine, Oxymorphone.
- Atropine with Dexmedetomidine, Glycopyrrolate, Ketamine, Midazolam, Morphine.
Alfaxalone and propofol are not mixed with other drugs in the syringe (both are given alone, propofol being a lipid emulsion). Diazepam is given alone. Ketamine, midazolam and dexmedetomidine are compatible with each other, which is why the three-drug feline sedation combinations work in one syringe.
Drug-by-drug IV compatibility notes (dogs and cats)
Quick summaries for the drugs most often asked about, generated from the checker's data. Open a drug for its compatible, incompatible and caution partners; use the checker above for the note and source behind any pair.
Fentanyl IV compatibility (dogs and cats)
Compatible (68): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amikacin, Aminophylline, Ampicillin, Atracurium, Atropine, Ca chloride, Ca gluconate, Cefazolin, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexamethasone SP, Dexmedetomidine, Diltiazem, Dobutamine, Dolasetron, Dopamine, Esmolol, Famotidine, Fluconazole, Furosemide, Gentamicin, Glycopyrrolate, Heparin, Hydrocortisone, Hydromorphone, Imipenem-cilastatin, Insulin, KCl, Ketamine, Labetalol, Lidocaine, LRS / Hartmann's, Maintenance fluid, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, NAC, NaHCO3, Naloxone, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Penicillin G, Phenobarbital, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Thiopental, Tobramycin, Vancomycin, Vasopressin, Vecuronium.
Incompatible, never share a line (13): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Omeprazole, Oxyglobin, Pantoprazole, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (17): Amino acids, Amiodarone, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Methylprednisolone SS, Paracetamol IV, Parenteral nutrition, Pentobarbital, Pimobendan inj, Prednisolone SS, Trimethoprim-sulfa.
No published data with 63 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Morphine IV compatibility (dogs and cats)
Compatible (74): 0.45% NaCl, 0.9% NaCl, Acepromazine, Adrenaline, Amikacin, Amiodarone, Ampicillin, Atracurium, Atropine, B complex, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexamethasone SP, Dexmedetomidine, Diphenhydramine, Dobutamine, Dolasetron, Dopamine, Erythromycin, Esmolol, Fentanyl, Fluconazole, Gentamicin, Glycopyrrolate, Heparin, Hydrocortisone, Hydromorphone, Imipenem-cilastatin, Insulin, KCl, Ketamine, Labetalol, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Meropenem, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, NAC, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Rocuronium, Tobramycin, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
Incompatible, never share a line (13): Ampicillin-sulbactam, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Omeprazole, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (18): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Furosemide, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Pantoprazole, Paracetamol IV, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Prednisolone SS, Thiopental.
No published data with 56 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Methadone IV compatibility (dogs and cats)
Compatible (10): 0.45% NaCl, 0.9% NaCl, Acepromazine, D5W, Dexamethasone SP, Dexmedetomidine, Ketamine, Lidocaine, Metoclopramide, Midazolam.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (20): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Plasma-Lyte, Propofol, Thiopental, Trimethoprim-sulfa.
No published data with 120 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Hydromorphone IV compatibility (dogs and cats)
Compatible (57): 0.45% NaCl, 0.9% NaCl, Adrenaline, Ampicillin, Ca gluconate, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Ciprofloxacin, Clindamycin, Cyclosporine, D5W, Diphenhydramine, Dobutamine, Dolasetron, Dopamine, Erythromycin, Fentanyl, Fluconazole, Furosemide, Gentamicin, Glycopyrrolate, Heparin, Hydrocortisone, Imipenem-cilastatin, Insulin, K phosphate, KCl, Ketamine, Labetalol, Lorazepam, LRS / Hartmann's, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Penicillin G, Piperacillin-tazobactam, Procainamide, Propofol, Remifentanil, Tobramycin, Trimethoprim-sulfa, Vancomycin, Vasopressin.
Incompatible, never share a line (15): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, NaHCO3, Oxyglobin, Pentobarbital, Phenobarbital, Tetanus antitoxin, Thiopental, Vinblastine, Vincristine.
Caution, check first (17): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Dexamethasone SP, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Lidocaine, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Prednisolone SS.
No published data with 72 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Butorphanol IV compatibility (dogs and cats)
Compatible (9): 0.45% NaCl, 0.9% NaCl, Acepromazine, D5W, Dexmedetomidine, Glycopyrrolate, Ketamine, Midazolam, Tiletamine-zolazepam.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (20): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Plasma-Lyte, Propofol, Thiopental, Trimethoprim-sulfa.
No published data with 121 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Buprenorphine IV compatibility (dogs and cats)
Compatible (8): 0.45% NaCl, 0.9% NaCl, Acepromazine, D5W, Dexmedetomidine, Glycopyrrolate, LRS / Hartmann's, Midazolam.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (16): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Propofol, Trimethoprim-sulfa.
No published data with 126 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Ketamine IV compatibility (dogs and cats)
Compatible (39): 0.45% NaCl, 0.9% NaCl, Acepromazine, Adrenaline, Amiodarone, Atropine, Butorphanol, Cefazolin, Ceftazidime, Cefuroxime, Clindamycin, D5W, Dexamethasone SP, Dexmedetomidine, Dobutamine, Dolasetron, Dopamine, Fentanyl, Gentamicin, Hydrocortisone, Hydromorphone, KCl, Lidocaine, LRS / Hartmann's, Maintenance fluid, Methadone, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Ondansetron, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Propofol, Tiletamine-zolazepam, Tobramycin.
Incompatible, never share a line (19): Ampicillin, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Furosemide, Heparin, hIVIG, Insulin, K phosphate, Meropenem, NaHCO3, Oxyglobin, Tetanus antitoxin, Thiopental, Vinblastine, Vincristine.
Caution, check first (19): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Methylprednisolone SS, Omeprazole, Pantoprazole, Paracetamol IV, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Prednisolone SS, Trimethoprim-sulfa.
No published data with 84 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Lidocaine (lignocaine) IV compatibility (dogs and cats)
Compatible (51): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Ca chloride, Ca gluconate, Cefazolin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Ciprofloxacin, Clindamycin, Cyclosporine, D5W, Dexamethasone SP, Dexmedetomidine, Dobutamine, Dopamine, Famotidine, Fentanyl, Fluconazole, Furosemide, Gentamicin, Glycopyrrolate, Heparin, Hydrocortisone, Insulin, KCl, Ketamine, Labetalol, LRS / Hartmann's, Maintenance fluid, Methadone, Metoclopramide, Metronidazole, MgSO4, Midazolam, Morphine, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Remifentanil, Tobramycin, Vancomycin, Vasopressin.
Incompatible, never share a line (13): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Milrinone, NaHCO3, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (19): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Hydromorphone, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Methylprednisolone SS, Omeprazole, Pantoprazole, Paracetamol IV, Parenteral nutrition, Pimobendan inj, Prednisolone SS, Propofol, Trimethoprim-sulfa.
No published data with 78 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Dexmedetomidine / medetomidine IV compatibility (dogs and cats)
Compatible (53): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Ampicillin, Atracurium, Atropine, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Ceftazidime, Cefuroxime, Cyclosporine, D5W, Dobutamine, Dolasetron, Dopamine, Famotidine, Fentanyl, Fluconazole, Gentamicin, Glycopyrrolate, Heparin, Imipenem-cilastatin, Insulin, K phosphate, Ketamine, Lidocaine, LRS / Hartmann's, Maintenance fluid, Mannitol, Meropenem, Methadone, Metoclopramide, Metronidazole, MgSO4, Midazolam, Morphine, NaHCO3, Nalbuphine, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Phenylephrine, Plasma-Lyte, Remifentanil, Rocuronium, Tiletamine-zolazepam, Tobramycin, Vasopressin, Vecuronium.
Incompatible, never share a line (12): Amphotericin B, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (22): Amino acids, Carprofen, Cosyntropin (ACTH), Esomeprazole, Furosemide, Intralipid 20%, Iodinated contrast, Ketoprofen, Labetalol, Maropitant, Milrinone, Omeprazole, Pantoprazole, Paracetamol IV, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Procainamide, Propofol, Thiopental, Trimethoprim-sulfa.
No published data with 74 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Acepromazine IV compatibility (dogs and cats)
Compatible (9): 0.45% NaCl, 0.9% NaCl, Buprenorphine, Butorphanol, D5W, Ketamine, Methadone, Morphine, Oxymorphone.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (17): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Propofol, Trimethoprim-sulfa.
No published data with 124 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Midazolam IV compatibility (dogs and cats)
Compatible (55): 0.45% NaCl, 0.9% NaCl, Adrenaline, Alfaxalone, Amiodarone, Atracurium, Atropine, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Cefazolin, Ceftriaxone, Cimetidine, Ciprofloxacin, Cisatracurium, Cyclosporine, D5W, Dexmedetomidine, Dolasetron, Dopamine, Esmolol, Fentanyl, Fluconazole, Gentamicin, Heparin, Hydromorphone, Insulin, K phosphate, KCl, Ketamine, Labetalol, Lidocaine, LRS / Hartmann's, Methadone, Metoclopramide, Metronidazole, MgSO4, Milrinone, Morphine, NAC, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxymorphone, Penicillin G, Procainamide, Propofol, Remifentanil, Rocuronium, Tobramycin, Vancomycin, Vasopressin, Vecuronium.
Incompatible, never share a line (25): Aminophylline, Ampicillin, Blood products, Carboplatin, Ceftazidime, Cefuroxime, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Esomeprazole, Furosemide, hIVIG, Hydrocortisone, Imipenem-cilastatin, NaHCO3, Omeprazole, Oxyglobin, Pantoprazole, Piperacillin-tazobactam, Tetanus antitoxin, Thiopental, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (20): Amino acids, Amphotericin B, Carprofen, Cefoxitin, Cosyntropin (ACTH), Dexamethasone SP, Dobutamine, Famotidine, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Methylprednisolone SS, Paracetamol IV, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Plasma-Lyte, Prednisolone SS.
No published data with 61 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Diazepam IV compatibility (dogs and cats)
Compatible (1): Levetiracetam.
Incompatible, never share a line (156): 0.45% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Blood products, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carboplatin, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Cisplatin, Clindamycin, Cosyntropin (ACTH), Cyclophosphamide, Cyclosporine, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxorubicin, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, hIVIG, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Intralipid 20%, Iodinated contrast, K phosphate, KCl, Ketamine, Ketoprofen, Labetalol, Lidocaine, Lorazepam, Maintenance fluid, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxyglobin, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Tetanus antitoxin, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vinblastine, Vincristine, Vitamin K1.
Caution, check first (4): 0.9% NaCl, D5W, LRS / Hartmann's, Plasma-Lyte.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Propofol IV compatibility (dogs and cats)
Compatible (36): 0.9% NaCl, Adrenaline, Aminophylline, Ampicillin, Ca gluconate, Ceftazidime, Cefuroxime, Clindamycin, Cyclosporine, D5W, Dopamine, Esmolol, Fentanyl, Fluconazole, Furosemide, Glycopyrrolate, Heparin, Hydrocortisone, Hydromorphone, Insulin, KCl, Ketamine, Labetalol, LRS / Hartmann's, Mannitol, MgSO4, Midazolam, Milrinone, Morphine, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Remifentanil, Thiopental, Vecuronium.
Incompatible, never share a line (19): Atracurium, Blood products, Ca chloride, Carboplatin, Ciprofloxacin, Cisatracurium, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Gentamicin, hIVIG, Metronidazole, Oxyglobin, Plasma-Lyte, Tetanus antitoxin, Tobramycin, Vinblastine, Vincristine.
Caution, check first (106): 0.45% NaCl, Acepromazine, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atropine, B complex, Buprenorphine, Butorphanol, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftriaxone, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Cosyntropin (ACTH), Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esomeprazole, Ethanol, Etomidate, Famotidine, Flumazenil, Fomepizole, Gelatin colloid, Glucagon, HES colloid, Hydralazine, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Intralipid 20%, Iodinated contrast, K phosphate, Ketoprofen, Levetiracetam, Lidocaine, Lorazepam, Maintenance fluid, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Na phosphate, NAC, Nalbuphine, Naloxone, Neostigmine, Omeprazole, Ondansetron, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Pralidoxime, Prednisolone SS, Procainamide, Propranolol, Rocuronium, Terbutaline, Thiamine, Tiletamine-zolazepam, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vitamin K1.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Alfaxalone IV compatibility (dogs and cats)
Compatible (5): 0.45% NaCl, 0.9% NaCl, D5W, LRS / Hartmann's, Midazolam.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (16): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Propofol, Trimethoprim-sulfa.
No published data with 129 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Tiletamine-zolazepam (Telazol / Zoletil) IV compatibility (dogs and cats)
Compatible (3): Butorphanol, Dexmedetomidine, Ketamine.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (19): 0.9% NaCl, Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), D5W, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Propofol, Trimethoprim-sulfa.
No published data with 128 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Pentobarbital IV compatibility (dogs and cats)
Compatible (6): 0.45% NaCl, 0.9% NaCl, D5W, LRS / Hartmann's, Phenobarbital, Thiopental.
Incompatible, never share a line (17): Blood products, Carboplatin, Cefoxitin, Cimetidine, Cisplatin, Cyclophosphamide, Diazepam, Doxapram, Doxorubicin, Glycopyrrolate, hIVIG, Hydromorphone, Nalbuphine, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (35): Adrenaline, Amino acids, Amphotericin B, Atropine, Butorphanol, Carprofen, Chlorphenamine, Cosyntropin (ACTH), Dexmedetomidine, Diltiazem, Diphenhydramine, Dobutamine, Dopamine, Esomeprazole, Fentanyl, Insulin, Intralipid 20%, Iodinated contrast, Ketamine, Ketoprofen, Maropitant, Methadone, Metoclopramide, Midazolam, Morphine, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa, Vancomycin.
No published data with 103 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Adrenaline (epinephrine) IV compatibility (dogs and cats)
Compatible (54): 0.45% NaCl, 0.9% NaCl, Amiodarone, Atracurium, Ca chloride, Ca gluconate, Cefazolin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Dobutamine, Dopamine, Esmolol, Famotidine, Fentanyl, Fluconazole, Furosemide, Gentamicin, Heparin, Hydrocortisone, Hydromorphone, Insulin, KCl, Ketamine, Labetalol, Lidocaine, LRS / Hartmann's, Maintenance fluid, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, NAC, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Tobramycin, Vancomycin, Vasopressin, Vecuronium.
Incompatible, never share a line (16): Aminophylline, Ampicillin, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, NaHCO3, Omeprazole, Oxyglobin, Tetanus antitoxin, Thiopental, Vinblastine, Vincristine.
Caution, check first (18): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Dexamethasone SP, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Methylprednisolone SS, Pantoprazole, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Prednisolone SS, Trimethoprim-sulfa.
No published data with 73 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Noradrenaline (norepinephrine) IV compatibility (dogs and cats)
Compatible (50): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Ca chloride, Ca gluconate, Cefazolin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Cisatracurium, Clindamycin, D5W, Dexmedetomidine, Dobutamine, Dopamine, Esmolol, Famotidine, Fentanyl, Fluconazole, Furosemide, Heparin, Hydrocortisone, Hydromorphone, KCl, Labetalol, Lidocaine, LRS / Hartmann's, Maintenance fluid, Meropenem, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, NAC, Nitroglycerin, Nitroprusside, Ondansetron, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Tobramycin, Vancomycin, Vasopressin, Vecuronium.
Incompatible, never share a line (16): Aminophylline, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Insulin, NaHCO3, Omeprazole, Oxyglobin, Tetanus antitoxin, Thiopental, Vinblastine, Vincristine.
Caution, check first (18): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Dexamethasone SP, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Methylprednisolone SS, Pantoprazole, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Prednisolone SS, Trimethoprim-sulfa.
No published data with 77 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Dopamine IV compatibility (dogs and cats)
Compatible (63): 0.45% NaCl, 0.9% NaCl, Adrenaline, Aminophylline, Amiodarone, Atracurium, B complex, Ca chloride, Ca gluconate, Cefotaxime, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Diphenhydramine, Dobutamine, Erythromycin, Esmolol, Famotidine, Fentanyl, Fluconazole, Gentamicin, Heparin, Hydrocortisone, Hydromorphone, KCl, Ketamine, Labetalol, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, NAC, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Tobramycin, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
Incompatible, never share a line (18): Ampicillin, Blood products, Carboplatin, Cefazolin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Furosemide, hIVIG, Insulin, NaHCO3, Omeprazole, Oxyglobin, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (17): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Dexamethasone SP, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Pantoprazole, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Prednisolone SS, Thiopental.
No published data with 63 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Dobutamine IV compatibility (dogs and cats)
Compatible (39): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Atracurium, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Dopamine, Famotidine, Fentanyl, Fluconazole, Gentamicin, Hydromorphone, Ketamine, Labetalol, Lidocaine, LRS / Hartmann's, Maintenance fluid, Metoclopramide, Metronidazole, Milrinone, Morphine, NAC, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Plasma-Lyte, Procainamide, Remifentanil, Tobramycin, Vancomycin, Vasopressin, Vecuronium.
Incompatible, never share a line (27): Aminophylline, Ampicillin, Blood products, Ca chloride, Ca gluconate, Carboplatin, Cefazolin, Ceftriaxone, Cefuroxime, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Furosemide, Heparin, hIVIG, Hydralazine, K phosphate, NaHCO3, Omeprazole, Oxyglobin, Penicillin G, Piperacillin-tazobactam, Tetanus antitoxin, Thiopental, Vinblastine, Vincristine.
Caution, check first (24): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Dexamethasone SP, Esomeprazole, Hydrocortisone, Insulin, Intralipid 20%, Iodinated contrast, KCl, Ketoprofen, Maropitant, Methylprednisolone SS, MgSO4, Midazolam, Pantoprazole, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Prednisolone SS, Propofol, Trimethoprim-sulfa.
No published data with 71 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Vasopressin IV compatibility (dogs and cats)
Compatible (46): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Ca chloride, Ca gluconate, Cefazolin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Ciprofloxacin, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Dobutamine, Dopamine, Famotidine, Fentanyl, Fluconazole, Gentamicin, Heparin, Hydrocortisone, Hydromorphone, K phosphate, KCl, Labetalol, Lidocaine, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Penicillin G, Piperacillin-tazobactam, Procainamide, Remifentanil, Rocuronium, Tobramycin, Vancomycin.
Incompatible, never share a line (12): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Furosemide, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (18): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Insulin, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Propofol, Trimethoprim-sulfa.
No published data with 85 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Atropine IV compatibility (dogs and cats)
Compatible (14): 0.45% NaCl, 0.9% NaCl, Cimetidine, D5W, Dexmedetomidine, Fentanyl, Glycopyrrolate, Ketamine, LRS / Hartmann's, Maintenance fluid, Midazolam, Morphine, Ondansetron, Plasma-Lyte.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (19): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, NaHCO3, Omeprazole, Pantoprazole, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Propofol, Thiopental, Trimethoprim-sulfa.
No published data with 117 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Glycopyrrolate IV compatibility (dogs and cats)
Compatible (19): 0.45% NaCl, 0.9% NaCl, Atropine, Buprenorphine, Butorphanol, Cimetidine, D5W, Dexmedetomidine, Diphenhydramine, Fentanyl, Hydromorphone, Lidocaine, Maintenance fluid, Morphine, Nalbuphine, Ondansetron, Oxymorphone, Plasma-Lyte, Propofol.
Incompatible, never share a line (18): Blood products, Carboplatin, Chloramphenicol, Cisplatin, Cyclophosphamide, Dexamethasone SP, Diazepam, Doxorubicin, hIVIG, Methylprednisolone SS, NaHCO3, Oxyglobin, Pentobarbital, Phenobarbital, Tetanus antitoxin, Thiopental, Vinblastine, Vincristine.
Caution, check first (17): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Hydrocortisone, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Prednisolone SS, Trimethoprim-sulfa.
No published data with 107 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Amiodarone IV compatibility (dogs and cats)
Compatible (33): Adrenaline, Atracurium, Ca chloride, Ciprofloxacin, Clindamycin, D5W, Dexmedetomidine, Dobutamine, Dopamine, Esmolol, Famotidine, Fluconazole, Gentamicin, Insulin, KCl, Ketamine, Labetalol, Lidocaine, Metronidazole, Midazolam, Milrinone, Morphine, NAC, Nitroglycerin, Nitroprusside, Noradrenaline, Procainamide, Remifentanil, Rocuronium, Tobramycin, Vancomycin, Vasopressin, Vecuronium.
Incompatible, never share a line (30): 0.9% NaCl, Aminophylline, Ampicillin, Blood products, Carboplatin, Cefazolin, Ceftazidime, Ceftriaxone, Cefuroxime, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Furosemide, Heparin, hIVIG, Hydrocortisone, K phosphate, LRS / Hartmann's, Meropenem, MgSO4, Na phosphate, NaHCO3, Omeprazole, Oxyglobin, Piperacillin-tazobactam, Plasma-Lyte, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (16): Amino acids, Amphotericin B, Ca gluconate, Carprofen, Cosyntropin (ACTH), Esomeprazole, Fentanyl, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 82 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Diltiazem IV compatibility (dogs and cats)
Compatible (9): 0.45% NaCl, 0.9% NaCl, Cefoxitin, Cimetidine, D5W, Fentanyl, LRS / Hartmann's, Maintenance fluid, Plasma-Lyte.
Incompatible, never share a line (13): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Furosemide, hIVIG, NaHCO3, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (20): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Dexamethasone SP, Esomeprazole, Hydrocortisone, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Methylprednisolone SS, Omeprazole, Pantoprazole, Parenteral nutrition, Pentobarbital, Pimobendan inj, Prednisolone SS, Propofol, Trimethoprim-sulfa.
No published data with 119 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Pimobendan injectable IV compatibility (dogs and cats)
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (150): 0.45% NaCl, 0.9% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cosyntropin (ACTH), Cyclosporine, D5W, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Intralipid 20%, Iodinated contrast, K phosphate, KCl, Ketamine, Ketoprofen, Labetalol, Levetiracetam, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Piperacillin-tazobactam, Plasma-Lyte, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Furosemide (frusemide) IV compatibility (dogs and cats)
Compatible (50): 0.45% NaCl, 0.9% NaCl, Adrenaline, Aminophylline, Ampicillin, B complex, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Clindamycin, Cyclosporine, D5W, Famotidine, Fentanyl, Heparin, Hydrocortisone, Hydromorphone, Insulin, K phosphate, KCl, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Meropenem, Methylprednisolone SS, Metronidazole, MgSO4, Na phosphate, NAC, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Thiopental, Tobramycin, Vitamin K1.
Incompatible, never share a line (36): Amiodarone, Blood products, Carboplatin, Chlorpromazine, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Diltiazem, Diphenhydramine, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxorubicin, Erythromycin, Esmolol, Fluconazole, hIVIG, Hydralazine, Ketamine, Labetalol, Metoclopramide, Midazolam, Milrinone, Omeprazole, Ondansetron, Oxyglobin, Rocuronium, Tetanus antitoxin, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vinblastine, Vincristine.
Caution, check first (17): Amikacin, Amino acids, Amphotericin B, Carprofen, Cisatracurium, Cosyntropin (ACTH), Dexmedetomidine, Esomeprazole, Gentamicin, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Morphine, Pantoprazole, Parenteral nutrition, Pimobendan inj.
No published data with 58 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Mannitol 20% IV compatibility (dogs and cats)
Compatible (11): 0.45% NaCl, 0.9% NaCl, Cisatracurium, D5W, Dexmedetomidine, Dopamine, Furosemide, Gentamicin, Ondansetron, Propofol, Remifentanil.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (16): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Trimethoprim-sulfa.
No published data with 123 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Hypertonic saline 7.2% IV compatibility (dogs and cats)
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (19): 0.9% NaCl, Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), D5W, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Propofol, Trimethoprim-sulfa.
No published data with 131 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Heparin (unfractionated) IV compatibility (dogs and cats)
Compatible (62): 0.45% NaCl, 0.9% NaCl, Adrenaline, Aminophylline, Ampicillin, B complex, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Clindamycin, Cyclosporine, D5W, Dexamethasone SP, Dexmedetomidine, Dolasetron, Dopamine, Esmolol, Fentanyl, Fluconazole, Furosemide, Hydrocortisone, Hydromorphone, Imipenem-cilastatin, Insulin, K phosphate, KCl, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Meropenem, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Thiopental, Vasopressin, Vecuronium, Vitamin K1.
Incompatible, never share a line (23): Amikacin, Amiodarone, Blood products, Carboplatin, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Dobutamine, Doxorubicin, Doxycycline, Erythromycin, Famotidine, Gentamicin, hIVIG, Ketamine, Omeprazole, Oxyglobin, Tetanus antitoxin, Tobramycin, Vancomycin, Vinblastine, Vincristine.
Caution, check first (19): Amino acids, Amphotericin B, Atracurium, Carprofen, Cisatracurium, Cosyntropin (ACTH), Esomeprazole, Hydralazine, Intralipid 20%, Iodinated contrast, Ketoprofen, Labetalol, Maropitant, Pantoprazole, Paracetamol IV, Parenteral nutrition, Pimobendan inj, Prednisolone SS, Trimethoprim-sulfa.
No published data with 57 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Tranexamic acid IV compatibility (dogs and cats)
Compatible (6): 0.45% NaCl, 0.9% NaCl, D5W, LRS / Hartmann's, Maintenance fluid, Plasma-Lyte.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (15): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 129 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Potassium chloride IV compatibility (dogs and cats)
Compatible (70): 0.45% NaCl, 0.9% NaCl, Adrenaline, Aminophylline, Amiodarone, Ampicillin, Atracurium, B complex, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexamethasone SP, Diphenhydramine, Dolasetron, Dopamine, Erythromycin, Esmolol, Famotidine, Fentanyl, Fluconazole, Furosemide, Gentamicin, Heparin, Hydralazine, Hydrocortisone, Hydromorphone, Imipenem-cilastatin, Insulin, K phosphate, Ketamine, Labetalol, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Meropenem, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Thiopental, Tobramycin, Vancomycin, Vasopressin, Vitamin K1.
Incompatible, never share a line (13): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Glucagon, hIVIG, Oxyglobin, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (18): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Dobutamine, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Methylprednisolone SS, NAC, Omeprazole, Pantoprazole, Paracetamol IV, Parenteral nutrition, Pimobendan inj, Prednisolone SS.
No published data with 60 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Potassium phosphate IV compatibility (dogs and cats)
Compatible (31): 0.45% NaCl, 0.9% NaCl, B complex, Cefazolin, Clindamycin, D5W, Dexmedetomidine, Diphenhydramine, Erythromycin, Esmolol, Furosemide, Heparin, Hydrocortisone, Hydromorphone, Insulin, KCl, Labetalol, Maintenance fluid, Metoclopramide, Metronidazole, Midazolam, Milrinone, Nitroprusside, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Remifentanil, Tobramycin, Vancomycin, Vasopressin, Vitamin K1.
Incompatible, never share a line (20): Amiodarone, Blood products, Ca chloride, Ca gluconate, Carboplatin, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Dobutamine, Doxorubicin, hIVIG, Ketamine, Lorazepam, LRS / Hartmann's, Oxyglobin, Rocuronium, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (16): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, MgSO4, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 94 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Magnesium sulfate IV compatibility (dogs and cats)
Compatible (56): 0.45% NaCl, 0.9% NaCl, Adrenaline, Ampicillin, B complex, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Diphenhydramine, Dolasetron, Dopamine, Erythromycin, Esmolol, Famotidine, Fentanyl, Fluconazole, Furosemide, Gentamicin, Heparin, Hydrocortisone, Hydromorphone, Imipenem-cilastatin, Insulin, KCl, Ketamine, Labetalol, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Metoclopramide, Metronidazole, Midazolam, Milrinone, Morphine, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Tobramycin, Trimethoprim-sulfa, Vancomycin, Vasopressin.
Incompatible, never share a line (20): Amiodarone, Blood products, Ca chloride, Carboplatin, Ceftriaxone, Cefuroxime, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Doxycycline, hIVIG, Methylprednisolone SS, Na phosphate, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine, Vitamin K1.
Caution, check first (21): Amino acids, Amphotericin B, Ca gluconate, Carprofen, Cosyntropin (ACTH), Dexamethasone SP, Dobutamine, Enrofloxacin, Esomeprazole, Intralipid 20%, Iodinated contrast, K phosphate, Ketoprofen, Marbofloxacin, Maropitant, NaHCO3, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Prednisolone SS.
No published data with 64 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Calcium gluconate 10% IV compatibility (dogs and cats)
Compatible (50): 0.45% NaCl, 0.9% NaCl, Adrenaline, B complex, Ca chloride, Cefazolin, Cefotaxime, Ceftazidime, Cefuroxime, Ciprofloxacin, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Diphenhydramine, Dopamine, Erythromycin, Famotidine, Fentanyl, Furosemide, Gentamicin, Heparin, Hydromorphone, Insulin, KCl, Labetalol, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Metoclopramide, Metronidazole, Midazolam, Milrinone, Morphine, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Tobramycin, Vancomycin, Vasopressin, Vitamin K1.
Incompatible, never share a line (22): Amphotericin B, Blood products, Carboplatin, Ceftriaxone, Cisplatin, Cyclophosphamide, Diazepam, Dobutamine, Doxorubicin, Doxycycline, Fluconazole, hIVIG, K phosphate, Methylprednisolone SS, Na phosphate, NaHCO3, Oxyglobin, Pamidronate, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (19): Amino acids, Amiodarone, Carprofen, Cosyntropin (ACTH), Dexamethasone SP, Enrofloxacin, Esomeprazole, Hydrocortisone, Intralipid 20%, Iodinated contrast, Ketoprofen, Marbofloxacin, Maropitant, MgSO4, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Prednisolone SS.
No published data with 70 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Sodium bicarbonate 8.4% IV compatibility (dogs and cats)
Compatible (37): 0.45% NaCl, 0.9% NaCl, Aminophylline, Cefazolin, Ceftazidime, Ceftriaxone, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Erythromycin, Esmolol, Famotidine, Fentanyl, Fluconazole, Furosemide, Gentamicin, Heparin, Hydrocortisone, KCl, Lorazepam, Maintenance fluid, Methylprednisolone SS, Metronidazole, Milrinone, Morphine, Nitroglycerin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Tobramycin, Vancomycin, Vasopressin, Vitamin K1.
Incompatible, never share a line (40): Adrenaline, Amiodarone, Blood products, Ca chloride, Ca gluconate, Carboplatin, Cefotaxime, Cefuroxime, Chlorpromazine, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Diltiazem, Diphenhydramine, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxorubicin, Doxycycline, Enrofloxacin, Ephedrine, Glycopyrrolate, hIVIG, Hydromorphone, Imipenem-cilastatin, Ketamine, Labetalol, Lidocaine, Midazolam, Noradrenaline, Ondansetron, Oxyglobin, Phenylephrine, Propranolol, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (24): Amino acids, Amphotericin B, Atropine, Carprofen, Cisatracurium, Cosyntropin (ACTH), Dexamethasone SP, Digoxin, Esomeprazole, Insulin, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Metoclopramide, MgSO4, Omeprazole, Oxytocin, Pantoprazole, Parenteral nutrition, Pimobendan inj, Thiamine, Thiopental.
No published data with 60 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Dextrose 50% IV compatibility (dogs and cats)
Compatible (6): 0.45% NaCl, 0.9% NaCl, D5W, LRS / Hartmann's, Maintenance fluid, Plasma-Lyte.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (15): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 129 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Insulin (regular / neutral) IV compatibility (dogs and cats)
Compatible (54): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Ampicillin, Atracurium, B complex, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Clindamycin, D5W, Dexmedetomidine, Erythromycin, Esmolol, Fentanyl, Fluconazole, Furosemide, Gentamicin, Heparin, Hydrocortisone, Hydromorphone, Imipenem-cilastatin, K phosphate, KCl, Lidocaine, Lorazepam, LRS / Hartmann's, Meropenem, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, Nitroglycerin, Nitroprusside, Ondansetron, Penicillin G, Procainamide, Propofol, Remifentanil, Tobramycin, Vancomycin, Vecuronium, Vitamin K1.
Incompatible, never share a line (20): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Diphenhydramine, Dopamine, Doxorubicin, hIVIG, Ketamine, Labetalol, Noradrenaline, Omeprazole, Oxyglobin, Piperacillin-tazobactam, Rocuronium, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (19): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Dobutamine, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, NaHCO3, Pantoprazole, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Plasma-Lyte, Thiopental, Vasopressin.
No published data with 68 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Glucagon IV compatibility (dogs and cats)
Compatible (1): D5W.
Incompatible, never share a line (17): 0.45% NaCl, 0.9% NaCl, Blood products, Ca chloride, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, KCl, LRS / Hartmann's, Oxyglobin, Plasma-Lyte, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (15): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 128 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Maropitant IV compatibility (dogs and cats)
Compatible (1): Metoclopramide.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (149): 0.45% NaCl, 0.9% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cosyntropin (ACTH), Cyclosporine, D5W, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Intralipid 20%, Iodinated contrast, K phosphate, KCl, Ketamine, Ketoprofen, Labetalol, Levetiracetam, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Marbofloxacin, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Plasma-Lyte, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Metoclopramide IV compatibility (dogs and cats)
Compatible (51): 0.45% NaCl, 0.9% NaCl, Amikacin, B complex, Ca gluconate, Cefazolin, Ceftriaxone, Cefuroxime, Cimetidine, Ciprofloxacin, Clindamycin, Cyclosporine, D5W, Dexamethasone SP, Dexmedetomidine, Diphenhydramine, Dobutamine, Dolasetron, Dopamine, Famotidine, Fentanyl, Fluconazole, Gentamicin, Heparin, Hydrocortisone, Hydromorphone, Imipenem-cilastatin, Insulin, K phosphate, KCl, Ketamine, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Maropitant, Meropenem, Methadone, Methylprednisolone SS, Metronidazole, MgSO4, Midazolam, Morphine, Na phosphate, Ondansetron, Oxytocin, Piperacillin-tazobactam, Plasma-Lyte, Tobramycin, Vancomycin, Vitamin K1.
Incompatible, never share a line (19): Ampicillin, Ampicillin-sulbactam, Blood products, Carboplatin, Chloramphenicol, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Esomeprazole, Furosemide, hIVIG, Omeprazole, Oxyglobin, Pantoprazole, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (20): Amino acids, Amphotericin B, Carprofen, Cefotaxime, Ceftazidime, Cosyntropin (ACTH), Erythromycin, Intralipid 20%, Iodinated contrast, Ketoprofen, NaHCO3, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Pimobendan inj, Prednisolone SS, Propofol, Thiopental.
No published data with 71 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Ondansetron IV compatibility (dogs and cats)
Compatible (39): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amikacin, Atropine, Ca gluconate, Cefazolin, Cefoxitin, Ceftriaxone, Cimetidine, Clindamycin, D5W, Dexamethasone SP, Dexmedetomidine, Diphenhydramine, Dobutamine, Dopamine, Famotidine, Fentanyl, Gentamicin, Glycopyrrolate, Heparin, Hydromorphone, Imipenem-cilastatin, Insulin, KCl, Ketamine, Lidocaine, LRS / Hartmann's, Maintenance fluid, Mannitol, Metoclopramide, Metronidazole, MgSO4, Midazolam, Morphine, Noradrenaline, Plasma-Lyte, Vasopressin.
Incompatible, never share a line (23): Aminophylline, Ampicillin, Ampicillin-sulbactam, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Esomeprazole, Furosemide, hIVIG, Lorazepam, Meropenem, Methylprednisolone SS, NaHCO3, Omeprazole, Oxyglobin, Pantoprazole, Piperacillin-tazobactam, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (20): Amino acids, Amphotericin B, Carprofen, Chloramphenicol, Cosyntropin (ACTH), Doxycycline, Hydrocortisone, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Paracetamol IV, Parenteral nutrition, Pentobarbital, Phenobarbital, Pimobendan inj, Prednisolone SS, Propofol, Thiopental, Trimethoprim-sulfa.
No published data with 79 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Pantoprazole IV compatibility (dogs and cats)
Compatible (3): 0.9% NaCl, D5W, LRS / Hartmann's.
Incompatible, never share a line (16): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Dolasetron, Doxorubicin, Fentanyl, hIVIG, Metoclopramide, Midazolam, Ondansetron, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (142): 0.45% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cosyntropin (ACTH), Cyclosporine, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dopamine, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Intralipid 20%, Iodinated contrast, K phosphate, KCl, Ketamine, Ketoprofen, Labetalol, Levetiracetam, Lidocaine, Lorazepam, Maintenance fluid, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metronidazole, MgSO4, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Oxymorphone, Oxytocin, Pamidronate, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Plasma-Lyte, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Famotidine IV compatibility (dogs and cats)
Compatible (49): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Ampicillin, B complex, Ca chloride, Ca gluconate, Cefotaxime, Cefoxitin, Ceftazidime, Cefuroxime, Cimetidine, Clindamycin, Cyclosporine, D5W, Dexamethasone SP, Dexmedetomidine, Diphenhydramine, Dobutamine, Dolasetron, Dopamine, Erythromycin, Fentanyl, Fluconazole, Furosemide, Gentamicin, Hydrocortisone, Imipenem-cilastatin, KCl, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Metoclopramide, Metronidazole, MgSO4, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Plasma-Lyte, Procainamide, Tobramycin, Vasopressin, Vitamin K1.
Incompatible, never share a line (16): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Heparin, hIVIG, Hydralazine, Oxyglobin, Piperacillin-tazobactam, Rocuronium, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (22): Amino acids, Amphotericin B, Carprofen, Cefazolin, Ceftriaxone, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Labetalol, Maropitant, Methylprednisolone SS, Midazolam, Milrinone, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Prednisolone SS, Propofol, Vancomycin.
No published data with 74 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Cimetidine IV compatibility (dogs and cats)
Compatible (39): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amikacin, Ampicillin, Atropine, Cefazolin, Ceftriaxone, Clindamycin, D5W, Dexamethasone SP, Diltiazem, Diphenhydramine, Dobutamine, Dopamine, Esmolol, Famotidine, Fentanyl, Furosemide, Gentamicin, Glycopyrrolate, Heparin, Hydromorphone, Insulin, KCl, Labetalol, Lidocaine, LRS / Hartmann's, Maintenance fluid, Meropenem, Metoclopramide, Metronidazole, Midazolam, Morphine, Noradrenaline, Ondansetron, Plasma-Lyte, Vancomycin, Vasopressin.
Incompatible, never share a line (13): Amphotericin B, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Pentobarbital, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (15): Amino acids, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Phenobarbital, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 94 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Ampicillin IV compatibility (dogs and cats)
Compatible (25): 0.45% NaCl, 0.9% NaCl, B complex, Cimetidine, Clindamycin, Cyclosporine, Dexmedetomidine, Famotidine, Fentanyl, Furosemide, Heparin, Hydromorphone, Insulin, KCl, LRS / Hartmann's, Metronidazole, MgSO4, Milrinone, Morphine, Procainamide, Propofol, Remifentanil, Rocuronium, Vancomycin, Vitamin K1.
Incompatible, never share a line (30): Adrenaline, Amikacin, Amiodarone, Blood products, Ca chloride, Carboplatin, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Diphenhydramine, Dobutamine, Dolasetron, Dopamine, Doxorubicin, Fluconazole, Gentamicin, hIVIG, Ketamine, Lorazepam, Metoclopramide, Midazolam, Nitroprusside, Ondansetron, Oxyglobin, Tetanus antitoxin, Tobramycin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (15): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), D5W, Doxycycline, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj.
No published data with 91 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Ampicillin-sulbactam IV compatibility (dogs and cats)
Compatible (3): 0.45% NaCl, 0.9% NaCl, LRS / Hartmann's.
Incompatible, never share a line (18): Amikacin, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Dolasetron, Doxorubicin, Gentamicin, hIVIG, Metoclopramide, Morphine, Ondansetron, Oxyglobin, Tetanus antitoxin, Tobramycin, Vinblastine, Vincristine.
Caution, check first (17): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), D5W, Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa, Vancomycin.
No published data with 123 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Amoxicillin-clavulanate IV IV compatibility (dogs and cats)
Compatible (3): 0.45% NaCl, 0.9% NaCl, LRS / Hartmann's.
Incompatible, never share a line (15): Amikacin, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, D5W, Diazepam, Doxorubicin, Gentamicin, hIVIG, Oxyglobin, Tetanus antitoxin, Tobramycin, Vinblastine, Vincristine.
Caution, check first (15): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 128 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Cefazolin IV compatibility (dogs and cats)
Compatible (46): 0.45% NaCl, 0.9% NaCl, Adrenaline, B complex, Ca gluconate, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Clindamycin, Cyclosporine, D5W, Fentanyl, Fluconazole, Furosemide, Heparin, Hydrocortisone, Hydromorphone, Insulin, K phosphate, KCl, Ketamine, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Plasma-Lyte, Procainamide, Remifentanil, Vasopressin, Vitamin K1.
Incompatible, never share a line (24): Amikacin, Amiodarone, Blood products, Ca chloride, Carboplatin, Cefotaxime, Cisplatin, Cyclophosphamide, Diazepam, Diphenhydramine, Dobutamine, Dopamine, Doxorubicin, Erythromycin, Gentamicin, hIVIG, Hydralazine, Oxyglobin, Tetanus antitoxin, Tobramycin, Trimethoprim-sulfa, Vancomycin, Vinblastine, Vincristine.
Caution, check first (16): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Doxycycline, Esomeprazole, Famotidine, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol.
No published data with 75 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Cefoxitin IV compatibility (dogs and cats)
Compatible (15): 0.45% NaCl, 0.9% NaCl, D5W, Diltiazem, Famotidine, Fentanyl, Heparin, Hydromorphone, Insulin, KCl, LRS / Hartmann's, Metronidazole, MgSO4, Morphine, Ondansetron.
Incompatible, never share a line (15): Amikacin, Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Gentamicin, hIVIG, Oxyglobin, Pentobarbital, Tetanus antitoxin, Tobramycin, Vinblastine, Vincristine.
Caution, check first (16): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Midazolam, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 115 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Ceftriaxone IV compatibility (dogs and cats)
Compatible (42): 0.45% NaCl, 0.9% NaCl, Adrenaline, B complex, Cefazolin, Cefotaxime, Ceftazidime, Cefuroxime, Cimetidine, Cyclosporine, D5W, Dopamine, Erythromycin, Fentanyl, Furosemide, Heparin, Hydrocortisone, Hydromorphone, Insulin, KCl, Lidocaine, Lorazepam, Maintenance fluid, Methylprednisolone SS, Metoclopramide, Metronidazole, Midazolam, Milrinone, Morphine, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Plasma-Lyte, Procainamide, Remifentanil, Rocuronium, Vasopressin, Vitamin K1.
Incompatible, never share a line (27): Amikacin, Amiodarone, Blood products, Ca chloride, Ca gluconate, Carboplatin, Cisplatin, Clindamycin, Cyclophosphamide, Diazepam, Diphenhydramine, Dobutamine, Doxorubicin, Fluconazole, Gentamicin, hIVIG, Hydralazine, Labetalol, LRS / Hartmann's, MgSO4, Oxyglobin, Tetanus antitoxin, Tobramycin, Trimethoprim-sulfa, Vancomycin, Vinblastine, Vincristine.
Caution, check first (15): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Famotidine, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol.
No published data with 77 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Enrofloxacin IV compatibility (dogs and cats)
Compatible (3): 0.45% NaCl, 0.9% NaCl, D5W.
Incompatible, never share a line (12): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, NaHCO3, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (20): Amino acids, Amphotericin B, Ca chloride, Ca gluconate, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, MgSO4, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Propofol, Trimethoprim-sulfa.
No published data with 126 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Marbofloxacin IV compatibility (dogs and cats)
Compatible (3): 0.45% NaCl, 0.9% NaCl, D5W.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (20): Amino acids, Amphotericin B, Ca chloride, Ca gluconate, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, MgSO4, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Plasma-Lyte, Propofol, Trimethoprim-sulfa.
No published data with 127 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Metronidazole IV compatibility (dogs and cats)
Compatible (65): 0.45% NaCl, 0.9% NaCl, Adrenaline, Aminophylline, Amiodarone, Ampicillin, B complex, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Diphenhydramine, Dobutamine, Dopamine, Erythromycin, Esmolol, Famotidine, Fentanyl, Fluconazole, Furosemide, Gentamicin, Heparin, Hydralazine, Hydrocortisone, Hydromorphone, Insulin, K phosphate, KCl, Ketamine, Labetalol, Lidocaine, Lorazepam, Maintenance fluid, Methylprednisolone SS, Metoclopramide, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Piperacillin-tazobactam, Plasma-Lyte, Remifentanil, Rocuronium, Tobramycin, Trimethoprim-sulfa, Vancomycin, Vasopressin.
Incompatible, never share a line (15): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Meropenem, Oxyglobin, Penicillin G, Procainamide, Propofol, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (14): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, LRS / Hartmann's, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj.
No published data with 67 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Clindamycin IV compatibility (dogs and cats)
Compatible (57): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Ampicillin, B complex, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Ceftazidime, Cefuroxime, Cimetidine, Cyclosporine, D5W, Diphenhydramine, Dobutamine, Dopamine, Famotidine, Fentanyl, Furosemide, Gentamicin, Heparin, Hydrocortisone, Hydromorphone, Insulin, K phosphate, KCl, Ketamine, Labetalol, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Milrinone, Morphine, Na phosphate, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Ondansetron, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Tobramycin, Vancomycin, Vasopressin, Vitamin K1.
Incompatible, never share a line (15): Blood products, Carboplatin, Ceftriaxone, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Erythromycin, hIVIG, Oxyglobin, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (13): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj.
No published data with 76 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Gentamicin IV compatibility (dogs and cats)
Compatible (53): 0.45% NaCl, 0.9% NaCl, Adrenaline, Amiodarone, Atracurium, B complex, Ca chloride, Ca gluconate, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cyclosporine, D5W, Dexmedetomidine, Diphenhydramine, Dobutamine, Dopamine, Erythromycin, Esmolol, Famotidine, Fentanyl, Fluconazole, Hydromorphone, Insulin, KCl, Ketamine, Labetalol, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, NAC, NaHCO3, Nitroglycerin, Nitroprusside, Ondansetron, Oxytocin, Plasma-Lyte, Procainamide, Remifentanil, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
Incompatible, never share a line (26): Amoxicillin-clavulanate, Ampicillin, Ampicillin-sulbactam, Blood products, Carboplatin, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Heparin, hIVIG, Imipenem-cilastatin, Oxyglobin, Penicillin G, Piperacillin-tazobactam, Propofol, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (16): Amino acids, Amphotericin B, Carprofen, Chloramphenicol, Cosyntropin (ACTH), Esomeprazole, Furosemide, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Meropenem, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj.
No published data with 66 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Amikacin IV compatibility (dogs and cats)
Compatible (9): 0.45% NaCl, 0.9% NaCl, Cimetidine, D5W, Fentanyl, LRS / Hartmann's, Metoclopramide, Morphine, Ondansetron.
Incompatible, never share a line (25): Amoxicillin-clavulanate, Ampicillin, Ampicillin-sulbactam, Blood products, Carboplatin, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Heparin, hIVIG, Imipenem-cilastatin, Meropenem, Oxyglobin, Penicillin G, Piperacillin-tazobactam, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (17): Amino acids, Amphotericin B, Carprofen, Chloramphenicol, Cosyntropin (ACTH), Esomeprazole, Furosemide, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 110 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Meropenem IV compatibility (dogs and cats)
Compatible (20): 0.45% NaCl, 0.9% NaCl, Cimetidine, Cyclosporine, D5W, Dexmedetomidine, Diphenhydramine, Fluconazole, Furosemide, Heparin, Insulin, KCl, LRS / Hartmann's, Maintenance fluid, Metoclopramide, Milrinone, Morphine, Noradrenaline, Plasma-Lyte, Vancomycin.
Incompatible, never share a line (19): Amikacin, Amiodarone, B complex, Blood products, Carboplatin, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Ketamine, Metronidazole, Ondansetron, Oxyglobin, Tetanus antitoxin, Tobramycin, Vinblastine, Vincristine.
Caution, check first (17): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Doxycycline, Esomeprazole, Gentamicin, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 105 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Trimethoprim-sulfamethoxazole IV IV compatibility (dogs and cats)
Compatible (14): 0.9% NaCl, Atracurium, D5W, Esmolol, Hydromorphone, Labetalol, Lorazepam, LRS / Hartmann's, Metronidazole, MgSO4, Morphine, Piperacillin-tazobactam, Remifentanil, Vecuronium.
Incompatible, never share a line (38): Ampicillin, B complex, Blood products, Ca gluconate, Carboplatin, Cefazolin, Cefotaxime, Ceftazidime, Ceftriaxone, Cefuroxime, Cisplatin, Clindamycin, Cyclophosphamide, Diazepam, Diphenhydramine, Dopamine, Doxorubicin, Famotidine, Fluconazole, Furosemide, Gentamicin, hIVIG, Hydrocortisone, Insulin, KCl, Methylprednisolone SS, Metoclopramide, Midazolam, NaHCO3, Oxyglobin, Oxytocin, Penicillin G, Tetanus antitoxin, Tobramycin, Vancomycin, Vinblastine, Vincristine, Vitamin K1.
Caution, check first (109): 0.45% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atropine, Buprenorphine, Butorphanol, Ca chloride, Carprofen, Cefoxitin, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Cosyntropin (ACTH), Cyclosporine, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Dipyrone, Dobutamine, Dolasetron, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esomeprazole, Ethanol, Etomidate, Fentanyl, Flumazenil, Fomepizole, Gelatin colloid, Glucagon, Glycopyrrolate, Heparin, HES colloid, Hydralazine, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Intralipid 20%, Iodinated contrast, K phosphate, Ketamine, Ketoprofen, Levetiracetam, Lidocaine, Maintenance fluid, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Milrinone, Na phosphate, NAC, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Plasma-Lyte, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Rocuronium, Terbutaline, Thiamine, Thiopental, Tiletamine-zolazepam, Tramadol, Tranexamic acid, Vasopressin.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Levetiracetam IV compatibility (dogs and cats)
Compatible (8): 0.45% NaCl, 0.9% NaCl, D5W, Diazepam, Lorazepam, LRS / Hartmann's, Maintenance fluid, Plasma-Lyte.
Incompatible, never share a line (10): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (15): Amino acids, Amphotericin B, Carprofen, Cosyntropin (ACTH), Esomeprazole, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 128 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Phenobarbital IV compatibility (dogs and cats)
Compatible (6): 0.45% NaCl, 0.9% NaCl, D5W, Fentanyl, LRS / Hartmann's, Pentobarbital.
Incompatible, never share a line (15): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxapram, Doxorubicin, Glycopyrrolate, hIVIG, Hydromorphone, Oxyglobin, Tetanus antitoxin, Vancomycin, Vinblastine, Vincristine.
Caution, check first (32): Adrenaline, Amino acids, Amphotericin B, Atropine, Butorphanol, Carprofen, Chlorphenamine, Cimetidine, Cosyntropin (ACTH), Dexmedetomidine, Diphenhydramine, Dobutamine, Dopamine, Esomeprazole, Insulin, Intralipid 20%, Iodinated contrast, Ketamine, Ketoprofen, Maropitant, Methadone, Metoclopramide, Midazolam, Morphine, Noradrenaline, Omeprazole, Ondansetron, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa.
No published data with 108 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Dexamethasone sodium phosphate IV compatibility (dogs and cats)
Compatible (19): 0.45% NaCl, 0.9% NaCl, Cimetidine, D5W, Diphenhydramine, Dolasetron, Famotidine, Fentanyl, Heparin, KCl, Ketamine, Lidocaine, LRS / Hartmann's, Maintenance fluid, Methadone, Metoclopramide, Morphine, Ondansetron, Plasma-Lyte.
Incompatible, never share a line (12): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, Glycopyrrolate, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (29): Adrenaline, Amino acids, Amphotericin B, Ca gluconate, Carprofen, Chlorphenamine, Ciprofloxacin, Cosyntropin (ACTH), Diltiazem, Dobutamine, Dopamine, Doxycycline, Esomeprazole, Hydromorphone, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, MgSO4, Midazolam, NaHCO3, Noradrenaline, Omeprazole, Pantoprazole, Parenteral nutrition, Pimobendan inj, Propofol, Trimethoprim-sulfa, Vancomycin.
No published data with 101 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Hydrocortisone sodium succinate IV compatibility (dogs and cats)
Compatible (46): 0.45% NaCl, 0.9% NaCl, Adrenaline, B complex, Cefazolin, Cefotaxime, Ceftazidime, Ceftriaxone, Cefuroxime, Clindamycin, Cyclosporine, D5W, Diphenhydramine, Dopamine, Erythromycin, Famotidine, Fentanyl, Fluconazole, Furosemide, Heparin, Hydromorphone, Insulin, K phosphate, KCl, Ketamine, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Metoclopramide, Metronidazole, MgSO4, Morphine, NaHCO3, Nitroglycerin, Nitroprusside, Noradrenaline, Oxytocin, Penicillin G, Piperacillin-tazobactam, Plasma-Lyte, Procainamide, Propofol, Remifentanil, Vasopressin, Vitamin K1.
Incompatible, never share a line (17): Amiodarone, Blood products, Carboplatin, Ciprofloxacin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Labetalol, Midazolam, Oxyglobin, Rocuronium, Tetanus antitoxin, Trimethoprim-sulfa, Vinblastine, Vincristine.
Caution, check first (21): Amino acids, Amphotericin B, Ca gluconate, Carprofen, Chlorphenamine, Cosyntropin (ACTH), Diltiazem, Dobutamine, Doxycycline, Esomeprazole, Glycopyrrolate, Intralipid 20%, Iodinated contrast, Ketoprofen, Maropitant, Omeprazole, Ondansetron, Pantoprazole, Parenteral nutrition, Pimobendan inj, Vancomycin.
No published data with 77 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Carprofen injection IV compatibility (dogs and cats)
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (148): 0.45% NaCl, 0.9% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cosyntropin (ACTH), Cyclosporine, D5W, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Intralipid 20%, Iodinated contrast, K phosphate, KCl, Ketamine, Labetalol, Levetiracetam, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Marbofloxacin, Maropitant, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Plasma-Lyte, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
No published data with 2 other listed items: give separately and flush. Open the checker above for the note and source behind any pair.
Intralipid 20% (lipid emulsion) IV compatibility (dogs and cats)
Compatible (1): Amino acids.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (149): 0.45% NaCl, 0.9% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cosyntropin (ACTH), Cyclosporine, D5W, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Iodinated contrast, K phosphate, KCl, Ketamine, Ketoprofen, Labetalol, Levetiracetam, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Plasma-Lyte, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Blood products (whole blood, pRBC, plasma) IV compatibility (dogs and cats)
Compatible (1): 0.9% NaCl.
Incompatible, never share a line (159): 0.45% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carboplatin, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Cisplatin, Clindamycin, Cosyntropin (ACTH), Cyclophosphamide, Cyclosporine, D5W, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Diazepam, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxorubicin, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, hIVIG, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Intralipid 20%, Iodinated contrast, K phosphate, KCl, Ketamine, Ketoprofen, Labetalol, Levetiracetam, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxyglobin, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Tetanus antitoxin, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vinblastine, Vincristine, Vitamin K1.
Caution, check first (1): Plasma-Lyte.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Parenteral nutrition IV compatibility (dogs and cats)
Compatible (1): Amino acids.
Incompatible, never share a line (11): Blood products, Carboplatin, Cisplatin, Cyclophosphamide, Diazepam, Doxorubicin, hIVIG, Oxyglobin, Tetanus antitoxin, Vinblastine, Vincristine.
Caution, check first (149): 0.45% NaCl, 0.9% NaCl, Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Clindamycin, Cosyntropin (ACTH), Cyclosporine, D5W, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Intralipid 20%, Iodinated contrast, K phosphate, KCl, Ketamine, Ketoprofen, Labetalol, Levetiracetam, Lidocaine, Lorazepam, LRS / Hartmann's, Maintenance fluid, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Plasma-Lyte, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vitamin K1.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Doxorubicin IV compatibility (dogs and cats)
Compatible (2): 0.9% NaCl, D5W.
Incompatible, never share a line (155): Acepromazine, Adrenaline, Albumin, Alfaxalone, Amikacin, Amino acids, Aminocaproic acid, Aminophylline, Amiodarone, Amoxicillin-clavulanate, Amphotericin B, Ampicillin, Ampicillin-sulbactam, Antivenom, Apomorphine, Atipamezole, Atracurium, Atropine, B complex, Blood products, Buprenorphine, Butorphanol, Ca chloride, Ca gluconate, Carboplatin, Carprofen, Cefazolin, Cefotaxime, Cefoxitin, Ceftazidime, Ceftriaxone, Cefuroxime, Chloramphenicol, Chlorphenamine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisatracurium, Cisplatin, Clindamycin, Cosyntropin (ACTH), Cyclophosphamide, Cyclosporine, Desmopressin, Dexamethasone SP, Dexmedetomidine, Dextrose 50%, Diazepam, Digoxin, Diltiazem, Diphenhydramine, Dipyrone, Dobutamine, Dolasetron, Dopamine, Doxapram, Doxycycline, Enrofloxacin, Ephedrine, Erythromycin, Esmolol, Esomeprazole, Ethanol, Etomidate, Famotidine, Fentanyl, Fluconazole, Flumazenil, Fomepizole, Furosemide, Gelatin colloid, Gentamicin, Glucagon, Glycopyrrolate, Heparin, HES colloid, hIVIG, Hydralazine, Hydrocortisone, Hydromorphone, Hyoscine butylbromide, Hypertonic saline, Imipenem-cilastatin, Insulin, Intralipid 20%, Iodinated contrast, K phosphate, KCl, Ketamine, Ketoprofen, Labetalol, Levetiracetam, Lidocaine, Lorazepam, Mannitol, Marbofloxacin, Maropitant, Meloxicam, Meropenem, Methadone, Methocarbamol, Methylene blue, Methylprednisolone SS, Metoclopramide, Metronidazole, MgSO4, Midazolam, Milrinone, Morphine, Na phosphate, NAC, NaHCO3, Nalbuphine, Naloxone, Neostigmine, Nitroglycerin, Nitroprusside, Noradrenaline, Omeprazole, Ondansetron, Oxyglobin, Oxymorphone, Oxytocin, Pamidronate, Pantoprazole, Paracetamol IV, Parenteral nutrition, Penicillin G, Pentobarbital, Phenobarbital, Phenylephrine, Pimobendan inj, Piperacillin-tazobactam, Pralidoxime, Prednisolone SS, Procainamide, Propofol, Propranolol, Remifentanil, Rocuronium, Terbutaline, Tetanus antitoxin, Thiamine, Thiopental, Tiletamine-zolazepam, Tobramycin, Tramadol, Tranexamic acid, Trimethoprim-sulfa, Vancomycin, Vasopressin, Vecuronium, Vinblastine, Vincristine, Vitamin K1.
Caution, check first (4): 0.45% NaCl, LRS / Hartmann's, Maintenance fluid, Plasma-Lyte.
No published data gaps: none, every listed pair is graded. Open the checker above for the note and source behind any pair.
Frequently asked questions
Can I run ceftriaxone in Hartmann's or Lactated Ringer's?
No. Ceftriaxone forms a precipitate with calcium, and Hartmann's/LRS contains calcium. Give ceftriaxone in 0.9% sodium chloride through a separate line, and flush well if it has to share a catheter with a calcium-containing fluid.
Can MLK or FLK go in the same bag?
Yes. Morphine (or fentanyl), lidocaine and ketamine are routinely combined in one crystalloid bag for a constant rate infusion in dogs. Use the CRI calculator for doses. In cats, lidocaine infusions are used with much more caution, so MK or FK combinations are usually preferred.
Can potassium chloride be added to Hartmann's or LRS?
Yes, potassium chloride is routinely added to any crystalloid bag. Mix the bag well by inverting it, use an infusion pump, and never exceed 0.5 mEq/kg/hour. Potassium phosphate is different: it must not go into a calcium-containing bag such as Hartmann's, so use 0.9% saline or dextrose for phosphate.
Can ketamine and midazolam be mixed in the same syringe?
Yes. Ketamine and midazolam are routinely drawn up together for induction or co-induction and are physically compatible. Ketamine, midazolam and dexmedetomidine are also labelled compatible with each other, which is why "kitty magic" style combinations work in one syringe.
Can dexmedetomidine and butorphanol go in one syringe?
Yes. The dexmedetomidine label lists butorphanol as compatible in the same syringe, and the combination (with or without ketamine) is a standard sedation protocol in dogs and cats.
Can furosemide and midazolam run through the same line?
No. Furosemide is alkaline and midazolam is acidic; hospital Y-site charts list them as incompatible (precipitate). The same applies to furosemide with dobutamine, dopamine, ondansetron, metoclopramide, esmolol and diltiazem. Give furosemide by a separate line or flush thoroughly before and after.
Which fluid can run with a blood transfusion?
Only 0.9% sodium chloride. Hartmann's or LRS contains calcium, which can overcome the citrate anticoagulant and clot the line; 5% dextrose is hypotonic and haemolyses red cells. Nothing else should be added to or run through a blood line.
Can metoclopramide go in the fluid bag?
Yes, a metoclopramide CRI is commonly added to the maintenance bag (protect it from light). Do not let that line meet furosemide, penicillins, cephalosporins at high concentration, sodium bicarbonate or a proton pump inhibitor, all of which can precipitate it. Note that metoclopramide is a weak antiemetic in cats.
Can an insulin CRI run alongside potassium supplementation?
Yes. Regular insulin is Y-site compatible with potassium chloride, potassium phosphate and dextrose. Make the insulin CRI in 0.9% saline and run 20 to 50 mL through the line first, because insulin adsorbs to plastic. Do not let insulin meet sodium bicarbonate.
Can maropitant be given through the fluid line?
There are no published compatibility data for maropitant with other drugs, and the product information says not to mix it. Give it slowly IV on its own, flushing the line before and after, or use a separate line.
What does "no data" mean, and can I still give the drug?
It means no published compatibility data was found for that pair. Do not assume the two can share a line. Give the drug separately: use another catheter or lumen, or pause the running infusion, flush the line with saline before and after the bolus, then restart.
Is Y-site the same as mixing in one syringe?
No. Y-site means the two solutions meet briefly in the tubing near the patient. Mixing in one bag or syringe means prolonged contact, so it needs stability data, not just physical compatibility. Use the "same bag / syringe" mode for that question; it is deliberately stricter.
How many IV lines does a critical patient need?
As many as it takes for no incompatible pair to share a line: often one peripheral line for the fluid plan and CRIs that are compatible with it, and a second peripheral or a multi-lumen jugular catheter for the rest (blood products, lipid, parenteral nutrition, ceftriaxone with a calcium fluid, and so on). Tick the drugs above and the checker suggests the fewest lines and lets you map them onto the catheters you have.
Does compatibility differ between dogs and cats?
Physical compatibility (precipitation, haze, emulsion breaking) is chemistry, so it is the same in dogs, cats and people. What differs is which drugs and doses are appropriate for each species; the species toggle shows those veterinary safety notes, for example lidocaine caution in cats and paracetamol being contraindicated in cats.
How do I print or download an IV line map for the kennel?
Tick the drugs, add a line for each catheter (click the limb on the body map), give each line its carrier fluid, drugs and rate notes, fill in the patient details and click "Print line map (A4)", "Download PDF" or "Download image (PNG)". You get an A4 sheet with the body map, numbered lines, what runs through each, compatibility status, the compatibility check for the selected drugs and sign-off boxes. The PDF and PNG are generated in your browser and nothing is uploaded, so they can go straight into the patient record or to a colleague.
Can I copy the plan into the patient's medical record?
Yes. "Copy notes for the record" puts a plain-text summary on your clipboard: patient details, species, mode, carrier fluid, every line with its site, carrier, drugs and compatibility status, the incompatible, caution and no-data pairs with their reasons, and the species safety notes. Paste it into your practice management system. You can preview and edit the text first, regenerate it after changing the plan, or download it as a .txt file.
Can I share a plan with a colleague?
Yes. "Copy link to this plan" puts a link on your clipboard that reopens the checker with the same species, carrier, drugs and lines selected. Nothing is stored on a server; the plan lives entirely in the link.
Can anything be given through a line carrying a blood transfusion?
No. Only the blood product and 0.9% sodium chloride should run through a transfusion line. Every other drug and fluid is graded incompatible with blood products in this tool for that reason: use another catheter or lumen, or pause the transfusion and flush before and after if there is truly no other access.
Can chemotherapy drugs (vincristine, doxorubicin, carboplatin) share an IV line?
No. Injectable chemotherapy is given through a dedicated, freshly placed first-stick catheter with its own giving set, never Y-sited with other drugs or piggybacked onto the fluid line, and the line is flushed with 0.9% saline before and after. Vincristine, vinblastine and doxorubicin are vesicants, so confirm patency first. Dilute only in the labelled diluent (usually 0.9% saline or 5% dextrose; cisplatin is saline-only and is not given to cats) and use closed-system cytotoxic handling. The checker grades every chemotherapy pair as incompatible for this reason and always plans a separate line.
Can ampicillin and gentamicin be given through the same line?
Not at the same time. Aminoglycosides (gentamicin, amikacin, tobramycin) and beta-lactams (ampicillin, amoxicillin-clavulanate, cefazolin, ceftriaxone, piperacillin) inactivate each other chemically when they mix, even though the mixture can look perfectly clear. Give them at different times through a flushed line, or through separate lines, and never in the same bag or syringe. Each of them can run beside a crystalloid on its own.
Do the lumens of a multi-lumen catheter count as separate lines?
Yes. The distal, medial and proximal lumens of a multi-lumen jugular catheter exit at different points along the catheter, so the solutions do not meet until they reach the bloodstream. Treat each lumen as its own line, which is how the line planner handles them: blood products, lipid, parenteral nutrition and incompatible drugs get their own lumen, and every lumen is labelled.
Can propofol be given through a line that is running fluids?
A propofol bolus is normally given through the injection port of a running crystalloid with a saline flush; hospital charts list it as Y-site compatible with 0.9% saline, Hartmann's and 5% dextrose and with common induction partners such as fentanyl, midazolam and ketamine, but not with Plasma-Lyte on one chart, and it is a lipid emulsion that should not be added to bags or mixed with other drugs. A propofol CRI runs from its own syringe pump line. Check the specific pair in the tool.
Where does the data come from?
Hospital Y-site compatibility charts derived from Trissel's Handbook on Injectable Drugs and the King Guide, manufacturer prescribing information, published compatibility studies and veterinary infusion references. Every graded pair shows its source, and every grade errs on the side of caution.
What the drug list covers
Carrier fluids (0.9% and 0.45% NaCl, Hartmann's/LRS, Plasma-Lyte 148 and Plasma-Lyte 56 / Normosol-M, 5% dextrose); analgesia, sedation and anaesthesia (fentanyl, remifentanil, morphine, methadone, hydromorphone, oxymorphone, butorphanol, buprenorphine, nalbuphine, tramadol, ketamine, tiletamine-zolazepam, lidocaine, dexmedetomidine and medetomidine, acepromazine, midazolam, diazepam, lorazepam, propofol, alfaxalone, etomidate, thiopental, neuromuscular blockers, neostigmine, meloxicam, carprofen, ketoprofen, dipyrone, paracetamol IV); cardiovascular and renal drugs (adrenaline, noradrenaline, dopamine, dobutamine, vasopressin, phenylephrine, ephedrine, milrinone, pimobendan, atropine, glycopyrrolate, amiodarone, procainamide, diltiazem, esmolol, propranolol, labetalol, digoxin, hydralazine, nitroprusside, nitroglycerin, furosemide, mannitol, hypertonic saline, heparin, tranexamic acid, aminocaproic acid, desmopressin); electrolytes and metabolic drugs (potassium chloride and phosphate, sodium phosphate, magnesium, calcium gluconate and chloride, sodium bicarbonate, dextrose 50%, insulin, glucagon, thiamine, B complex, vitamin K1); gastrointestinal drugs (maropitant, metoclopramide, ondansetron, dolasetron, chlorpromazine, erythromycin, pantoprazole, omeprazole, esomeprazole, famotidine, cimetidine, hyoscine butylbromide, apomorphine); antimicrobials (ampicillin, ampicillin-sulbactam, amoxicillin-clavulanate, penicillin G, piperacillin-tazobactam, cefazolin, cefoxitin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, meropenem, imipenem-cilastatin, enrofloxacin, marbofloxacin, ciprofloxacin, metronidazole, clindamycin, gentamicin, amikacin, tobramycin, trimethoprim-sulfa, doxycycline, chloramphenicol, vancomycin, fluconazole, amphotericin B); neurology drugs (levetiracetam, phenobarbital, pentobarbital, methocarbamol); steroids, antihistamines, respiratory drugs, iodinated contrast and cosyntropin; toxicology antidotes and reversal agents (N-acetylcysteine, Intralipid, naloxone, flumazenil, atipamezole, fomepizole, ethanol, pralidoxime, methylene blue, pamidronate, antivenom, tetanus antitoxin); colloids, blood products, Oxyglobin, human IVIG, amino acids and parenteral nutrition; and the common injectable chemotherapy agents (vincristine, vinblastine, doxorubicin, carboplatin, cisplatin, cyclophosphamide), which always get a dedicated line.
Related tools: CRI Calculator · IV Fluid Calculator · Emergency Drug Calculator · Anaesthetic Drug Calculator · Phosphate Supplementation Calculator · Blood Transfusion Calculator · All clinical calculators
How to read the grades & full source list
- Compatible: published data show the pair is physically compatible at usual concentrations. Still watch the line.
- Caution / variable: sources disagree, it depends on concentration, or only narrow conditions are compatible. Do not rely on it without checking.
- Incompatible: a precipitate, haze, emulsion break or loss of potency is reported, or a well-known chemical inactivation (for example aminoglycoside plus beta-lactam). Give separately and flush the line.
- No data: no compatibility data was found. The safe default is to give separately and flush between; do not assume compatibility.
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