Back to Blog

Vet Guide to Albon® (Sulfadimethoxine) in 2025: Safe Antibiotic Use for Dogs & Cats 🐾

  • 191 days ago
  • 9 min read

    In this article

Vet Guide to Albon® (Sulfadimethoxine) in 2025: Safe Antibiotic Use for Dogs & Cats 🐾

Vet Guide to Albon® (Sulfadimethoxine) in 2025 🐾

Hello! I’m Dr Duncan Houston, BVSc, founder of Ask A Vet. This comprehensive 2025 guide dives deep into Albon®—what it is, when to use it in dogs and cats, proper dosing, side effects, monitoring protocols, and expert safety tips. Let’s get started! 🩺

📘 What Is Albon®?

Albon® is the trade name for sulfadimethoxine, a long-acting sulfonamide antibiotic. It’s FDA-approved for use in dogs and cats, often to treat:

  • Protozoal coccidiosis (diarrhea in puppies/kittens) :contentReference[oaicite:3]{index=3}
  • Bacterial infections: respiratory, urinary, soft tissue, skin, wounds, abscesses :contentReference[oaicite:4]{index=4}

✅ Why Veterinarians Use It

Albon’s long duration (half-life ~13 hr in dogs) and oral form make it a convenient once-daily treatment :contentReference[oaicite:5]{index=5}. Liquid suspension (custard-flavored) and tablets are available, with IV/subQ injectable forms used in clinic :contentReference[oaicite:6]{index=6}.

📐 Dosing Guidelines

Dogs & Cats

  • Initial dose: 25 mg/lb (55 mg/kg) once daily
  • Maintenance dose: 12.5 mg/lb (27.5 mg/kg) daily thereafter
  • Treatment usually lasts 3–5 days or until 48 hrs after symptoms resolve :contentReference[oaicite:7]{index=7}.

Example: A 10 lb dog gets 1 tsp (5 mL) initially, then ½ tsp daily :contentReference[oaicite:8]{index=8}.

⚠️ Important Contraindications & Breeds to Watch

  • Pets with severe liver or kidney disease, dehydration, bladder/urinary stones :contentReference[oaicite:9]{index=9}
  • Pets allergic to sulfonamides, thiazides, or sulfonylureas :contentReference[oaicite:10]{index=10}
  • Sensitive breeds like Dobermans, Samoyeds, Mini Schnauzers—higher side effect risk :contentReference[oaicite:11]{index=11}
  • Avoid in pregnant or nursing animals; cautious use in geriatric or frail pets :contentReference[oaicite:12]{index=12}

🛑 Side Effects & Risks

Common (mild)

  • Reduced appetite, vomiting, diarrhea :contentReference[oaicite:13]{index=13}
  • Increased thirst/urination, mouth sores, or skin rash :contentReference[oaicite:14]{index=14}
  • Sulfa crystal formation in urine—ensure plenty of water :contentReference[oaicite:15]{index=15}

Serious (rare)

  • Dry eye (KCS), liver inflammation, fever :contentReference[oaicite:16]{index=16}
  • Blood disorders: anemia, leukopenia, thrombocytopenia :contentReference[oaicite:17]{index=17}
  • Allergic reactions—hives, facial swelling, polyarthritis :contentReference[oaicite:18]{index=18}

🔬 Monitoring During Treatment

  • Baseline and periodic bloodwork for CBC, liver, kidney, and thyroid function
  • Monitor tear production; evaluate for KCS
  • Watch symptoms: appetite, urination, hydration, stool, behavior
  • Ensure good water intake to prevent urinary crystals :contentReference[oaicite:19]{index=19}

🗓️ Missed Dose Guidance

If a dose is missed, give it when remembered. If it’s within <12 hours of next dose, skip and resume schedule—never double dose :contentReference[oaicite:20]{index=20}.

💊 Overdose Info

High doses are generally well tolerated in dogs; diarrhea may occur with extremely large single doses (e.g., 3.2 g/kg). Still, contact your vet or poison helpline if you suspect overdose: Pet Poison Helpline 855‑764‑7661 or ASPCA 888‑426‑4435 :contentReference[oaicite:21]{index=21}.

🔐 Storage & Handling Tips

  • Store at 59–86 °F (15–30 °C), sealed, away from moisture/light :contentReference[oaicite:22]{index=22}
  • Shake oral suspension well before use
  • Handle with gloves if allergic—wash hands after dosing :contentReference[oaicite:23]{index=23}
  • Keep away from children and other pets; dispose properly when unused

🏡 Real-Life Care Scenarios

✅ Puppy with Coccidiosis

  • Initial dose 25 mg/lb once daily, then 12.5 mg/lb daily for 3–5 days
  • Support with hydration and gradual diet
  • Recheck stool and ensure symptomatic improvement

🚿 Dog with Skin Wound Infection

  • Tailor dose based on weight for 7–10 days
  • Clean wound, monitor for redness/swelling/drainage
  • Follow up with culture or adjust antibiotic if needed

❓ FAQs

Can I safely handle Albon® if allergic?

Wear gloves during administration and wash hands afterward—especially if you're allergic to sulfa drugs :contentReference[oaicite:24]{index=24}.

Why once daily?

Sulfadimethoxine’s prolonged blood concentration allows effective once-a-day dosing, making it more convenient than many antibiotics :contentReference[oaicite:25]{index=25}.

Can I use Albon® in cats?

Yes—FDA-approved for cats, including for coccidiosis and bacterial infections—but follow precise dosing due to metabolic differences :contentReference[oaicite:26]{index=26}.

📌 Final Takeaways

  • Albon® is a reliable sulfonamide antibiotic for dogs & cats, indicated for protozoal and bacterial infections.
  • Use exact dosing—25 mg/lb initially, then 12.5 mg/lb daily; treatment ends 48 hrs after symptom resolution.
  • Monitor for side effects—dry eye, blood disorders, allergies, urinary crystal formation.
  • Ensure hydration, periodic bloodwork, and safe storage/handling.
  • In overdose, diarrhea is most common; seek vet or poison guidance as needed.

Need help designing an antibiotic plan or monitoring Albon® therapy for your pet? Ask A Vet is available 24/7 for safe, evidence-based guidance. Download our app today for veterinary advice anytime. 🐶🐱❤️

Dog Approved
Build to Last
Easy to Clean
Vet-Designed & Tested
Adventure-ready
Quality Tested & Trusted
Dog Approved
Build to Last
Easy to Clean
Vet-Designed & Tested
Adventure-ready
Quality Tested & Trusted